Quantum Dots (QDs) are zero-dimensional nanomaterials with dimensions less than or close to the exciton Bohr radius. With the development of nanotechnology, metal sulfide QDs has attracted wide attention due to their unique optical, electrical and magnetic properties, which can be classified into transition metal-disulfide QDs (TMD QDs), II-VI QDs and IV-VI QDs. The ultrasonic method for the preparation of QDs has the advantages of high efficiency, environmental protection, easy control and scalability, and has gradually become one of the important techniques for the preparation of metal sulfide QDs. Metal sulfide QDs have excellent optoelectronic properties that are different from those of traditional bulk materials, and their superior and unique properties have led to in-depth research and applications in more fields in recent years, such as optoelectronic devices, bio-imaging, and photocatalysis. In this paper, an overview of the preparation of different metal sulfide QDs by ultrasonication is reviewed, and their properties and applications are summarized and concluded. Finally, an outlook on the preparation of metal sulfide quantum dots by ultrasonication is given.