Opto-Electronic Engineering, Volume. 52, Issue 6, 250049(2025)

Optical design and applications of endoscopic optical coherence tomography probe with large field of view

Haoyang Yu1,2, Jinyuan Hu1,2, Jingye Gu1,2, Sujian Wu1,2, Jinyu Fan1,2, Yi He1,2, and Guohua Shi1,2、*
Author Affiliations
  • 1School of Biomedical Engineering, University of Science and Technology of China, Suzhou, Jiangsu 215163, China
  • 2Jiangsu Key Laboratory of Medical Optics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu 215163, China
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    This study addresses the limitations of existing endoscopic optical coherence tomography (OCT) probes in field of view (FOV), resolution, and dimensions constraints by proposing a novel design for a large-FOV forward-scanning endoscopic probe. The probe employs an optical system comprising six spherical lenses with an outer diameter of 1.4 mm, integrated with piezoelectric ceramic-driven fiber scanning technology. Operating in the 1000-1100 nm wavelength range, it achieves a scanning FOV of 6.0 mm, a lateral resolution of 24 μm, and an axial resolution of 20 μm, while maintaining a compact mechanical outer diameter of merely 1.6 mm. A swept-source OCT system was developed to validate the probe’s performance through imaging experiments on ex vivo porcine eyes. Results demonstrate the probe’s capability to clearly distinguish iris, sclera, and retinal structures, as well as visualize retinal detachment phenomena. Comparative analyses with graded-index lens probes reveal superior FOV expansion and reduced imaging artifacts. The study confirms that this probe effectively integrates miniaturization, high-resolution imaging, and large-FOV advantages, providing a new solution for ophthalmic minimally invasive surgical navigation. Future research could focus on further reducing the outer diameter and integrating two-dimensional scanning functionality to enhance its clinical potential.

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    Haoyang Yu, Jinyuan Hu, Jingye Gu, Sujian Wu, Jinyu Fan, Yi He, Guohua Shi. Optical design and applications of endoscopic optical coherence tomography probe with large field of view[J]. Opto-Electronic Engineering, 2025, 52(6): 250049

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    Paper Information

    Category: Article

    Received: Feb. 23, 2025

    Accepted: Apr. 24, 2025

    Published Online: Sep. 3, 2025

    The Author Email: Guohua Shi (史国华)

    DOI:10.12086/oee.2025.250049

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