Optical Parameter Measurement Method for Mucosal Lesion Recognition in Spatially Resolved Sub-Diffusive Regime

Qi Zhang; Limin Zhang; Jingyi An; Jing Wang; chen Chen; Feng Gao

doi:10.3788/AOS202141.2417001

Acta Optica Sinica, Volume. 41, Issue 24, 2417001(2021)

Optical Parameter Measurement Method for Mucosal Lesion Recognition in Spatially Resolved Sub-Diffusive Regime

Qi Zhang¹, Limin Zhang^1,2、*, Jingyi An¹, Jing Wang³, chen Chen³, and Feng Gao^1,2

Author Affiliations

¹School of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China

²Tianjin Key Laboratory of Biomedical Detecting Techniques and Instruments, Tianjin 300072, China

³The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, China

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Figures & Tables(8)

Fig. 1. Diagrams of light transmission in mucosa, fiber ring subdivision, and photon emission. (a) Diagram of light transmission in mucosa; (b) diagram of fiber ring subdivision; (c) diagram of photon emission

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Fig. 2. Training diagram of BPNN model

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Fig. 3. Retrieved results of optical parameters obtained by simulation. (a)(d) μ_a; (b)(e) μ'_s; (c)(f) γ

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Fig. 4. Schematic of measurement system

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Fig. 5. Retrieved results of optical parameters obtained by phantom experiment. (a)(d) μ_a; (b)(e) μ'_s; (c)(f) γ

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Table 1. RMSE and rRMSE of optical parameters retrieved by 3D-LUT and BPNN for noise of 0 dB, 20 dB, and 30 dB

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Table 1. RMSE and rRMSE of optical parameters retrieved by 3D-LUT and BPNN for noise of 0 dB, 20 dB, and 30 dB

Noise /dB	Inversemodel	RMSE ofμ_a	RMSE of μ'_s	RMSE ofγ	rRMSE of μ_a /%	rRMSE ofμ'_s /%	rRMSE ofγ /%
0	3D-LUT	0.0800	0.1462	0.0152	2.7909	1.4944	0.8201
	BPNN	0.0382	0.0553	0.0051	1.0914	0.7220	0.2757
30	3D-LUT	0.0870	0.1481	0.0152	2.8355	1.5643	0.8248
	BPNN	0.0439	0.0516	0.0050	1.1510	0.6589	0.2689
20	3D-LUT	0.1521	0.1809	0.0173	3.2527	2.1773	0.9362
	BPNN	0.0918	0.0737	0.0067	1.6031	1.0252	0.3645

Table 2. Optical parameters of turbid phantoms
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Table 2. Optical parameters of turbid phantoms
Experimental No. μ_a /cm^-1 μ'_s /cm^-1 γ
1 0 7.0 2.251
2 0 13.3 2.251
3 1.1 7.0 2.251
4 1.6 8.9 2.011
5 1.6 13.3 2.251
6 1.6 17.8 2.011
7 2.1 13.3 2.251

Table 3. RMSE and rRMSE of retrieved optical parameters obtained by 3D-LUT and BPNN
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Table 3. RMSE and rRMSE of retrieved optical parameters obtained by 3D-LUT and BPNN
Inverse model RMSE of μ_a RMSE of μ'_s RMSE of γ rRMSE ofμ_a /% rRMSE ofμ'_s /% rRMSE ofγ /%
3D-LUT 0.3116 1.6497 0.0969 18.7491 11.8015 4.7094
BPNN 0.3227 1.5787 0.1387 20.5682 11.7490 6.6988

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Qi Zhang, Limin Zhang, Jingyi An, Jing Wang, chen Chen, Feng Gao. Optical Parameter Measurement Method for Mucosal Lesion Recognition in Spatially Resolved Sub-Diffusive Regime[J]. Acta Optica Sinica, 2021, 41(24): 2417001

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Paper Information

Category: Medical optics and biotechnology

Received: May. 11, 2021

Accepted: Jun. 28, 2021

Published Online: Nov. 30, 2021

The Author Email: Zhang Limin (zhanglm@tju.edu.cn)

DOI:10.3788/AOS202141.2417001

Topics

laser devices and laser physics

Lasers and Laser Optics

Laser physics

laser manufacturing

Instrumentation, Measurement and Metrology

Table 1. RMSE and rRMSE of optical parameters retrieved by 3D-LUT and BPNN for noise of 0 dB, 20 dB, and 30 dB

Table 1. RMSE and rRMSE of optical parameters retrieved by 3D-LUT and BPNN for noise of 0 dB, 20 dB, and 30 dB

Table 2. Optical parameters of turbid phantoms

Table 2. Optical parameters of turbid phantoms

Table 3. RMSE and rRMSE of retrieved optical parameters obtained by 3D-LUT and BPNN

Table 3. RMSE and rRMSE of retrieved optical parameters obtained by 3D-LUT and BPNN