Journal of Radiation Research and Radiation Processing, Volume. 40, Issue 5, 050303(2022)

Rectal and bladder dose prediction in volumetric modulated arc therapy for cervical cancer based on dose-volume histogram

Ping ZHENG and Dong WANG*
Author Affiliations
  • Room of Radiotherapy, Zigong First People's Hospital, Zigong 643000, China
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    Figures & Tables(6)
    Relationship between the intersection volume and the expansion distance: (a) 3D visualization; (b) the cross-sectional schematic diagram (the rectum for an example, as is similar to bladder) (color online)
    Contribution rates of feature vector
    Comparison of predicted and actual values: (a) bladder V40; (b) bladder D33; (c) rectum V40; (d) rectum D33
    Prediction relative error of validation set (color online)
    • Table 1. Dose limit of organs at risks

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      Table 1. Dose limit of organs at risks

      危及器官

      Organs at risk

      剂量体积限值

      Dose volume limit

      膀胱BladderV40<60%D33<45Gy
      直肠RectumV40<60%D33<45Gy
      左股骨头Femoral head_leftV45<5%V30<30%
      右股骨头Femoral head_rightV45<5%V30<30%
      小肠Small bowelV30<30%
      脊髓Spinal cordDmax<45 Gy
    • Table 2. Multivariate nonlinear regression model coefficients for predicting bladder and rectum dose

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      Table 2. Multivariate nonlinear regression model coefficients for predicting bladder and rectum dose

      系数 Coefficient膀胱 Bladder V40膀胱 Bladder D33直肠 Rectum V40直肠 Rectum D33
      C03.603 362.4025.963 401.62
      C1-30.10-682.54-10.64-389.58
      C20.66-3.090.1212.27
      C30.6610.360.608.57
      C4-22.15-666.55-0.68-216.20
      C50.00-21.540.240.51
      C6-0.20-1.36-0.16-2.54
      C7-133.99-3 560.82-46.59-2 332.70
      C84.74-6.27-2.08-133.89
      C910.48225.243.96123.89
      C10190.095 346.3959.623 215.10
      C11-0.9972.562.07244.57
      C12-13.48-409.14-3.73-230.82
      C139.67113.1412.82460.62
      C146.22154.241.87192.86
      C15-13.50-266.78-7.52-279.44
      C16-54.99-1 571.39-16.95-1 068.73
      C17-0.18169.402.86378.12
      C18-5.05-70.14-3.67112.73
      C19-2.90-39.86-2.74-703.22
      C2011.37-113.326.63-138.03
      C21-4.12-203.70-7.59217.48
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    Ping ZHENG, Dong WANG. Rectal and bladder dose prediction in volumetric modulated arc therapy for cervical cancer based on dose-volume histogram[J]. Journal of Radiation Research and Radiation Processing, 2022, 40(5): 050303

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    Paper Information

    Category: Research Articles

    Received: Apr. 2, 2022

    Accepted: May. 20, 2022

    Published Online: Nov. 3, 2022

    The Author Email: Dong WANG (1363030065@qq.com)

    DOI:10.11889/j.1000-3436.2022-0039

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