Research Progress on Epidemic Virus Detection Based on Surface‑Enhanced Raman Spectroscopy

Yi Liu; Nan Wang; Shaohua He; Jun Zhang; Shangyuan Feng; Duo Lin

doi:10.3788/CJL231604

Chinese Journal of Lasers, Volume. 51, Issue 9, 0907006(2024)

Research Progress on Epidemic Virus Detection Based on Surface‑Enhanced Raman Spectroscopy

Yi Liu, Nan Wang, Shaohua He, Jun Zhang, Shangyuan Feng, and Duo Lin^*

Key Laboratory of Optoelectronic Science and Technology for Medicine of Ministry of Education, College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, Fujian , China

show less

Abstract Get PDF(in Chinese)

References(118)

[1] Kirtane A R, Verma M, Karandikar P et al. Nanotechnology approaches for global infectious diseases[J]. Nature Nanotechnology, 16, 369-384(2021).

[2] Durmuş S, Ülgen K Ö. Comparative interactomics for virus-human protein-protein interactions: DNA viruses versus RNA viruses[J]. FEBS Open Bio, 7, 96-107(2017).

[3] Saviñon-Flores F, Méndez E, López-Castaños M et al. A review on SERS-based detection of human virus infections: influenza and coronavirus[J]. Biosensors, 11, 66(2021).

[4] Morens D M, Fauci A S. Emerging pandemic diseases: how we got to COVID-19[J]. Cell, 182, 1077-1092(2020).

[5] Xiao M, Tian F, Liu X et al. Virus detection: from state-of-the-art laboratories to smartphone-based point-of-care testing[J]. Advanced Science, 9, e2105904(2022).

[6] Lukose J, Barik A K, Mithun N et al. Raman spectroscopy for viral diagnostics[J]. Biophysical Reviews, 15, 199-221(2023).

[7] Lin C Y, Hwang D, Chiu N C et al. Increased detection of viruses in children with respiratory tract infection using PCR[J]. International Journal of Environmental Research and Public Health, 17, 564(2020).

[8] Liu S Q, Li X, Deng C L et al. Development and evaluation of one-step multiplex real-time RT-PCR assay for simultaneous detection of Zika virus and Chikungunya virus[J]. Journal of Medical Virology, 90, 389-396(2018).

[9] Ou T P, Yun C, Auerswald H et al. Improved detection of dengue and Zika viruses using multiplex RT-qPCR assays[J]. Journal of Virological Methods, 282, 113862(2020).

[10] Bustin S A, Nolan T. RT-qPCR testing of SARS-CoV-2: a primer[J]. International Journal of Molecular Sciences, 21, 3004(2020).

[11] Soroka M, Wasowicz B, Rymaszewska A. Loop-mediated isothermal amplification (LAMP): the better sibling of PCR?[J]. Cells, 10, 1931(2021).

[12] Cassedy A, Parle-McDermott A, O’Kennedy R. Virus detection: a review of the current and emerging molecular and immunological methods[J]. Frontiers in Molecular Biosciences, 8, 637559(2021).

[13] Sitjar J, Liao J D, Lee H et al. Detection of live SARS-CoV-2 virus and its variants by specially designed SERS-active substrates and spectroscopic analyses[J]. Analytica Chimica Acta, 1256, 341151(2023).

[14] Xu H X, Xu B, Xiong J C et al. Research progress of surface plasmon resonance and local surface plasmon resonance in virus detection[J]. Chinese Journal of Lasers, 49, 1507401(2022).

[15] Wang Y Q, Yan B, Chen L X. SERS tags: novel optical nanoprobes for bioanalysis[J]. Chemical Reviews, 113, 1391-1428(2013).

[16] Pérez-Jiménez A I, Lyu D Y, Lu Z X et al. Surface-enhanced Raman spectroscopy: benefits, trade-offs and future developments[J]. Chemical Science, 11, 4563-4577(2020).

[17] Sharma B, Frontiera R R, Henry A I et al. SERS: materials, applications, and the future[J]. Materials Today, 15, 16-25(2012).

[18] Porter M D, Lipert R J, Siperko L M et al. SERS as a bioassay platform: fundamentals, design, and applications[J]. Chemical Society Reviews, 37, 1001-1011(2008).

[19] Wang Z Y, Zong S F, Wu L et al. SERS-activated platforms for immunoassay: probes, encoding methods, and applications[J]. Chemical Reviews, 117, 7910-7963(2017).

[20] Zong C, Xu M X, Xu L J et al. Surface-enhanced Raman spectroscopy for bioanalysis: reliability and challenges[J]. Chemical Reviews, 118, 4946-4980(2018).

[21] Pilot R, Signorini R, Durante C et al. A review on surface-enhanced Raman scattering[J]. Biosensors, 9, 57(2019).

[22] Payne T D, Klawa S J, Jian T Y et al. Catching COVID: engineering peptide-modified surface-enhanced Raman spectroscopy sensors for SARS-CoV-2[J]. ACS Sensors, 6, 3436-3444(2021).

[23] Raman C V, Krishnan K S. A new type of secondary radiation[J]. Nature, 121, 501-502(1928).

[24] Itoh T, Procházka M, Dong Z C et al. Toward a new era of SERS and TERS at the nanometer scale: from fundamentals to innovative applications[J]. Chemical Reviews, 123, 1552-1634(2023).

[25] Das R S, Agrawal Y K. Raman spectroscopy: recent advancements, techniques and applications[J]. Vibrational Spectroscopy, 57, 163-176(2011).

[26] Fleischmann M, Hendra P J, McQuillan A J. Raman spectra of pyridine adsorbed at a silver electrode[J]. Chemical Physics Letters, 26, 163-166(1974).

[27] Jeanmaire D L, Duyne R P V. Surface Raman spectroelectrochemistry: part I. Heterocyclic, aromatic, and aliphatic amines adsorbed on the anodized silver electrode[J]. Journal of Electroanalytical Chemistry, 84, 1-20(1977).

[28] Kudelski A. Raman spectroscopy of surfaces[J]. Surface Science, 603, 1328-1334(2009).

[29] Cialla D, März A, Böhme R et al. Surface-enhanced Raman spectroscopy (SERS): progress and trends[J]. Analytical and Bioanalytical Chemistry, 403, 27-54(2012).

[30] Bell S E J, Charron G, Cortés E et al. Towards reliable and quantitative surface-enhanced Raman scattering (SERS): from key parameters to good analytical practice[J]. Angewandte Chemie: International Ed. in English, 59, 5454-5462(2020).

[31] Yang B, Jin S L, Guo S et al. Recent development of SERS technology: semiconductor-based study[J]. ACS Omega, 4, 20101-20108(2019).

[32] Louten J[M]. Essential human virology, 19-29(2016).

[33] Sanjuán R, Nebot M R, Chirico N et al. Viral mutation rates[J]. Journal of Virology, 84, 9733-9748(2010).

[34] Zhou P, Yang X L, Wang X G et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin[J]. Nature, 579, 270-273(2020).

[35] Loeffelholz M J, Tang Y W. Laboratory diagnosis of emerging human coronavirus infections - the state of the art[J]. Emerging Microbes & Infections, 9, 747-756(2020).

[36] Yang Y, Peng Y S, Lin C L et al. Human ACE2-functionalized gold “virus-trap” nanostructures for accurate capture of SARS-CoV-2 and single-virus SERS detection[J]. Nano-Micro Letters, 13, 109(2021).

[37] Zhang Z, Jiang S, Wang X T et al. A novel enhanced substrate for label-free detection of SARS-CoV-2 based on surface-enhanced Raman scattering[J]. Sensors and Actuators B, 359, 131568(2022).

[38] Marques A C, Pinheiro T, Morais M et al. Bottom-up microwave-assisted seed-mediated synthesis of gold nanoparticles onto nanocellulose to boost stability and high performance for SERS applications[J]. Applied Surface Science, 561, 150060(2021).

[39] Sarychev A K, Sukhanova A, Ivanov A V et al. Label-free detection of the receptor-binding domain of the SARS-CoV-2 spike glycoprotein at physiologically relevant concentrations using surface-enhanced Raman spectroscopy[J]. Biosensors, 12, 300(2022).

[40] Wu P, Luo X J, Xu Y H et al. Long-range SERS detection of the SARS-CoV-2 antigen on a well-ordered gold hexagonal nanoplate film[J]. Analytical Chemistry, 94, 17541-17550(2022).

[41] Leonardi A A, Sciuto E L, Lo Faro M J et al. Molecular fingerprinting of the omicron variant genome of SARS-CoV-2 by SERS spectroscopy[J]. Nanomaterials, 12, 2134(2022).

[42] Paria D, Kwok K S, Raj P et al. Label-free spectroscopic SARS-CoV-2 detection on versatile nanoimprinted substrates[J]. Nano Letters, 22, 3620-3627(2022).

[43] Ramachandran K, Daoudi K, Columbus S et al. Facile, Flexible, Fast’: highly sensitive and Low-cost paper sensor for real time spike protein sensing with SERS[J]. Materials Science and Engineering: B, 286, 115984(2022).

[44] Peng Y S, Lin C L, Li Y Y et al. Identifying infectiousness of SARS-CoV-2 by ultra-sensitive SnS2 SERS biosensors with capillary effect[J]. Matter, 5, 694-709(2022).

[45] Feng E D, Zheng T T, He X X et al. Plasmon-induced charge transfer-enhanced Raman scattering on a semiconductor: toward amplification-free quantification of SARS-CoV-2[J]. Angewandte Chemie: International Ed. in English, 62, e202309249(2023).

[46] Li T Y, Srivastava S, Liu J et al. Label-free SARS-CoV-2 detection platform based on surface-enhanced Raman spectroscopy with support vector machine spectral pattern recognition[J]. Engineered Science, 23, 862(2023).

[47] Qin J W, Tian X D, Liu S Y et al. Rapid classification of SARS-CoV-2 variant strains using machine learning-based label-free SERS strategy[J]. Talanta, 267, 125080(2024).

[48] Yeh Y J, Le T N, Hsiao W W W et al. Plasmonic nanostructure-enhanced Raman scattering for detection of SARS-CoV-2 nucleocapsid protein and spike protein variants[J]. Analytica Chimica Acta, 1239, 340651(2023).

[49] Mo W B, Wen J X, Huang J L et al. Classification of coronavirus spike proteins by deep-learning-based Raman spectroscopy and its interpretative analysis[J]. Journal of Applied Spectroscopy, 89, 1203-1211(2023).

[50] Lai S X, Liu Y, Fang S B et al. Ultrasensitive detection of SARS-CoV-2 antigen using surface-enhanced Raman spectroscopy-based lateral flow immunosensor[J]. Journal of Biophotonics, 16, e202300004(2023).

[51] Guan P C, Zhang H, Li Z Y et al. Rapid point-of-care assay by SERS detection of SARS-CoV-2 virus and its variants[J]. Analytical Chemistry, 94, 17795-17802(2022).

[52] Antoine D, Mohammadi M, Vitt M et al. Rapid, point-of-care scFv-SERS assay for femtogram level detection of SARS-CoV-2[J]. ACS Sensors, 7, 866-873(2022).

[53] Zhang M L, Li X D, Pan J L et al. Ultrasensitive detection of SARS-CoV-2 spike protein in untreated saliva using SERS-based biosensor[J]. Biosensors & Bioelectronics, 190, 113421(2021).

[54] Vedelago C, Li J R, Lowry K et al. A multiplexed SERS microassay for accurate detection of SARS-CoV-2 and variants of concern[J]. ACS Sensors, 8, 1648-1657(2023).

[55] Zhang J J, Miao X P, Song C Y et al. Non-enzymatic signal amplification-powered point-of-care SERS sensor for rapid and ultra-sensitive assay of SARS-CoV-2 RNA[J]. Biosensors & Bioelectronics, 212, 114379(2022).

[56] Lin X L, Weng Y L, Liu Y et al. Ratiometric SERS sensing chip for high precision and ultra-sensitive detection of SARS-CoV-2 RNA in human saliva[J]. Sensors and Actuators B: Chemical, 399, 134803(2024).

[57] Chen H, Park S G, Choi N et al. Sensitive detection of SARS-CoV-2 using a SERS-based aptasensor[J]. ACS Sensors, 6, 2378-2385(2021).

[58] Yin B H, Ho W K H, Zhang Q et al. Magnetic-responsive surface-enhanced Raman scattering platform with tunable hot spot for ultrasensitive virus nucleic acid detection[J]. ACS Applied Materials & Interfaces, 14, 4714-4724(2022).

[59] Gao Y K, Han Y K, Wang C et al. Rapid and sensitive triple-mode detection of causative SARS-CoV-2 virus specific genes through interaction between genes and nanoparticles[J]. Analytica Chimica Acta, 1154, 338330(2021).

[60] Wu Y X, Dang H J, Park S G et al. SERS-PCR assays of SARS-CoV-2 target genes using Au nanoparticles-internalized Au nanodimple substrates[J]. Biosensors & Bioelectronics, 197, 113736(2022).

[61] Tabarov A, Vitkin V, Andreeva O et al. Detection of A and B influenza viruses by surface-enhanced Raman scattering spectroscopy and machine learning[J]. Biosensors, 12, 1065(2022).

[62] Gribanyov D, Zhdanov G, Olenin A et al. SERS-based colloidal aptasensors for quantitative determination of influenza virus[J]. International Journal of Molecular Sciences, 22, 1842(2021).

[63] Kim H, Kang H, Kim H N et al. Development of 6E3 antibody-mediated SERS immunoassay for drug-resistant influenza virus[J]. Biosensors & Bioelectronics, 187, 113324(2021).

[64] Zhdanov G, Nyhrikova E, Meshcheryakova N et al. A combination of membrane filtration and raman-active DNA ligand greatly enhances sensitivity of SERS-based aptasensors for influenza a virus[J]. Frontiers in Chemistry, 10, 937180(2022).

[65] Wang X W, Li S, Qu H et al. SERS-based immunomagnetic bead for rapid detection of H5N1 influenza virus[J]. Influenza and Other Respiratory Viruses, 17, e13114(2023).

[66] Kukushkin V, Kristavchuk O, Andreev E et al. Aptamer-coated track-etched membranes with a nanostructured silver layer for single virus detection in biological fluids[J]. Frontiers in Bioengineering and Biotechnology, 10, 1076749(2023).

[67] Lu M D, Joung Y, Jeon C S et al. Dual-mode SERS-based lateral flow assay strips for simultaneous diagnosis of SARS-CoV-2 and influenza a virus[J]. Nano Convergence, 9, 39(2022).

[68] Garsuault D, El Messaoudi S, Prabakaran M et al. Detection of several respiratory viruses with Surface-Enhanced Raman Spectroscopy coupled with Artificial Intelligence[J]. Clinical Spectroscopy, 5, 100025(2023).

[69] Chen H, Park S K, Joung Y et al. SERS-based dual-mode DNA aptasensors for rapid classification of SARS-CoV-2 and influenza A/H1N1 infection[J]. Sensors and Actuators B, 355, 131324(2022).

[70] Liu Z Z, Wang C W, Zheng S et al. Simultaneously ultrasensitive and quantitative detection of influenza A virus, SARS-CoV-2, and respiratory syncytial virus via multichannel magnetic SERS-based lateral flow immunoassay[J]. Nanomedicine: Nanotechnology, Biology, and Medicine, 47, 102624(2023).

[71] Liang J J, Wu L, Wang Y Q et al. SERS/photothermal-based dual-modal lateral flow immunoassays for sensitive and simultaneous antigen detection of respiratory viral infections[J]. Sensors and Actuators B: Chemical, 389, 133875(2023).

[72] Anwar S, Khawar M B, Ovais M et al. Gold nanocubes based optical detection of HIV-1 DNA via surface enhanced Raman spectroscopy[J]. Journal of Pharmaceutical and Biomedical Analysis, 226, 115242(2023).

[73] Yadav S, Senapati S, Desai D P et al. Portable and sensitive Ag nanorods based SERS platform for rapid HIV-1 detection and tropism determination[J]. Colloids and Surfaces B, 198, 111477(2021).

[74] Yadav S, Senapati S, Kulkarni S S et al. A SERS based clinical study on HIV-1 viral load quantification and determination of disease prognosis[J]. Journal of Photochemistry and Photobiology B, 239, 112629(2023).

[75] Winder N, Gohar S, Muthana M. Norovirus: an overview of virology and preventative measures[J]. Viruses, 14, 2811(2022).

[76] Achadu O J, Abe F, Li T C et al. Molybdenum trioxide quantum dot-encapsulated nanogels for virus detection by surface-enhanced Raman scattering on a 2D substrate[J]. ACS Applied Materials & Interfaces, 13, 27836-27844(2021).

[77] Achadu O J, Abe F, Hossain F et al. Sulfur-doped carbon dots@polydopamine-functionalized magnetic silver nanocubes for dual-modality detection of norovirus[J]. Biosensors & Bioelectronics, 193, 113540(2021).

[78] Maasoumy B, Wedemeyer H. Natural history of acute and chronic hepatitis C[J]. Best Practice & Research. Clinical Gastroenterology, 26, 401-412(2012).

[79] Kashif M, Majeed M I, Hanif M A et al. Surface Enhanced Raman Spectroscopy of the serum samples for the diagnosis of Hepatitis C and prediction of the viral loads[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 242, 118729(2020).

[80] Rafiq S, Majeed M I, Nawaz H et al. Surface-enhanced Raman spectroscopy for analysis of PCR products of viral RNA of hepatitis C patients[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 259, 119908(2021).

[81] Sang S W, Yue Y J, Wang Y G et al. The epidemiology and evolutionary dynamics of massive dengue outbreak in China, 2019[J]. Frontiers in Microbiology, 14, 1156176(2023).

[82] Wiwanitkit V. Concurrent malaria and dengue infection: a brief summary and comment[J]. Asian Pacific Journal of Tropical Biomedicine, 1, 326-327(2011).

[83] Farokhinejad F, Li J R, Hugo L E et al. Detection of dengue virus 2 with single infected mosquito resolution using yeast affinity bionanofragments and plasmonic SERS nanoboxes[J]. Analytical Chemistry, 94, 14177-14184(2022).

[84] Song C Y, Zhang J J, Liu Y et al. Highly sensitive SERS assay of DENV gene via a cascade signal amplification strategy of localized catalytic hairpin assembly and hybridization chain reaction[J]. Sensors and Actuators B, 325, 128970(2020).

[85] Jacob S S, Lukose J, Bankapur A et al. Micro-Raman spectroscopy study of optically trapped erythrocytes in malaria, dengue and leptospirosis infections[J]. Frontiers in Medicine, 9, 858776(2022).

[86] Tripathi M N, Jangir P, Aakriti et al. A novel approach for rapid and sensitive detection of Zika virus utilizing silver nanoislands as SERS platform[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 302, 123045(2023).

[87] Masmejan S, Musso D, Vouga M et al. Zika virus[J]. Pathogens, 9, 898(2020).

[88] Jia X F, Liu Z Z, Peng Y J et al. Automatic and sensitive detection of West Nile virus non-structural protein 1 with a portable SERS-LFIA detector[J]. Mikrochimica Acta, 188, 206(2021).

[89] Kaján G L, Doszpoly A, Tarján Z L et al. Virus-host coevolution with a focus on animal and human DNA viruses[J]. Journal of Molecular Evolution, 88, 41-56(2020).

[90] Schiller J T, Lowy D R. An introduction to virus infections and human cancer[J]. Recent Results in Cancer Research, 217, 1-11(2021).

[91] Seeger C, Mason W S. Molecular biology of hepatitis B virus infection[J]. Virology, 479/480, 672-686(2015).

[92] Kamińska A, Witkowska E, Winkler K et al. Detection of Hepatitis B virus antigen from human blood: SERS immunoassay in a microfluidic system[J]. Biosensors & Bioelectronics, 66, 461-467(2015).

[93] Du Y W, Ji S F, Dong Q Y et al. Amplification-free detection of HBV DNA mediated by CRISPR-Cas12a using surface-enhanced Raman spectroscopy[J]. Analytica Chimica Acta, 1245, 340864(2023).

[94] Batool F, Nawaz H, Majeed M I et al. SERS-based viral load quantification of hepatitis B virus from PCR products[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 255, 119722(2021).

[95] Karagoz A, Tombuloglu H, Alsaeed M et al. Monkeypox (mpox) virus: classification, origin, transmission, genome organization, antiviral drugs, and molecular diagnosis[J]. Journal of Infection and Public Health, 16, 531-541(2023).

[96] Zhang Z, Jiang H, Jiang S et al. Rapid detection of the monkeypox virus genome and antigen proteins based on surface-enhanced Raman spectroscopy[J]. ACS Applied Materials & Interfaces, 15, 34419-34426(2023).

[97] Yu Q, Li J X, Zheng S et al. Molybdenum disulfide-loaded multilayer AuNPs with colorimetric-SERS dual-signal enhancement activities for flexible immunochromatographic diagnosis of monkeypox virus[J]. Journal of Hazardous Materials, 459, 132136(2023).

[98] Dunmire S K, Verghese P S, Balfour H H, Jr. Primary Epstein-Barr virus infection[J]. Journal of Clinical Virology, 102, 84-92(2018).

[99] Houen G, Trier N H. Epstein-Barr virus and systemic autoimmune diseases[J]. Frontiers in Immunology, 11, 587380(2021).

[100] Tiwari D, Jakhmola S, Pathak D K et al. Temporal in vitro Raman spectroscopy for monitoring replication kinetics of Epstein-Barr virus infection in glial cells[J]. ACS Omega, 5, 29547-29560(2020).

[101] Sun J L, Wang R, Wang L et al. Visual/quantitative SERS biosensing chip based on Au-decorated polystyrene sphere microcavity arrays[J]. Sensors and Actuators B: Chemical, 388, 133869(2023).

[102] McGeoch D J, Rixon F J, Davison A J. Topics in herpesvirus genomics and evolution[J]. Virus Research, 117, 90-104(2006).

[103] Pezzotti G, Ohgitani E, Imamura H et al. Raman multi-omic snapshot and statistical validation of structural differences between herpes simplex type I and Epstein-Barr viruses[J]. International Journal of Molecular Sciences, 24, 15567(2023).

[104] Gallardo J, Pérez-Illana M, Martín-González N et al. Adenovirus structure: what is new?[J]. International Journal of Molecular Sciences, 22, 5240(2021).

[105] Greber U F, Flatt J W. Adenovirus entry: from infection to immunity[J]. Annual Review of Virology, 6, 177-197(2019).

[106] Chang C W, Liao J D, Shiau A L et al. Non-labeled virus detection using inverted triangular Au nano-cavities arrayed as SERS-active substrate[J]. Sensors and Actuators B: Chemical, 156, 471-478(2011).

[107] Kukushkin V, Ambartsumyan O, Subekin A et al. Multiplex lithographic SERS aptasensor for detection of several respiratory viruses in one pot[J]. International Journal of Molecular Sciences, 24, 8081(2023).

[108] Yin L J, Man S L, Ye S Y et al. CRISPR-Cas based virus detection: recent advances and perspectives[J]. Biosensors & Bioelectronics, 193, 113541(2021).

[109] Ma L, Zhang W L, Yin L J et al. A SERS-signalled, CRISPR/Cas-powered bioassay for amplification-free and anti-interference detection of SARS-CoV-2 in foods and environmental samples using a single tube-in-tube vessel[J]. Journal of Hazardous Materials, 452, 131195(2023).

[110] Su A L, Liu Y, Cao X M et al. A universal CRISPR/Cas12a-mediated AuNPs aggregation-based surface-enhanced Raman scattering (CRISPR/Cas-SERS) platform for virus gene detection[J]. Sensors and Actuators B: Chemical, 369, 132295(2022).

[111] Su A L, Liu Y, Cao X M et al. Direct virus gene detection: a CRISPR/dCas9-mediated surface-enhanced Raman scattering strategy with enzyme-catalyzed signal amplification[J]. Analytical Chemistry, 95, 5927-5936(2023).

[112] Wang H M, Su A L, Bao C X et al. A CRISPR/Cas12a-SERS platform for amplification-free detection of African swine fever virus genes[J]. Talanta, 267, 125225(2024).

[113] Liang J J, Teng P J, Xiao W et al. Application of the amplification-free SERS-based CRISPR/Cas12a platform in the identification of SARS-CoV-2 from clinical samples[J]. Journal of Nanobiotechnology, 19, 273(2021).

[114] Wang W, Ma P Y, Song D Q. Applications of surface-enhanced Raman spectroscopy based on portable Raman spectrometers: a review of recent developments[J]. Luminescence, 37, 1822-1835(2022).

[115] Kaladharan K, Chen K H, Chen P H et al. Dual-clamped one-pot SERS-based biosensors for rapid and sensitive detection of SARS-CoV-2 using portable Raman spectrometer[J]. Sensors and Actuators B, 393, 134172(2023).

[116] Ansah I B, An T, Yang J Y et al. Electrochemical synthesis of 3D plasmonic-molecule nanocomposite materials for in situ label-free molecular detections[J]. Advanced Materials Interfaces, 8, 2101201(2021).

[117] Pramanik A, Gao Y, Patibandla S et al. The rapid diagnosis and effective inhibition of coronavirus using spike antibody attached gold nanoparticles[J]. Nanoscale Advances, 3, 1588-1596(2021).

[118] Liu F X, Zhang L H, Huang X. Application of Raman spectroscopy in cancer diagnosis[J]. Laser & Optoelectronics Progress, 59, 0617016(2022).

Tools

Get Citation

Copy Citation Text

Yi Liu, Nan Wang, Shaohua He, Jun Zhang, Shangyuan Feng, Duo Lin. Research Progress on Epidemic Virus Detection Based on Surface‑Enhanced Raman Spectroscopy[J]. Chinese Journal of Lasers, 2024, 51(9): 0907006

Download Citation

EndNote(RIS)BibTex Plain Text

Set citation alerts for article

Save article for my favorites

Paper Information

Category: biomedical photonics and laser medicine

Received: Dec. 29, 2023

Accepted: Feb. 19, 2024

Published Online: Apr. 26, 2024

The Author Email: Lin Duo (duo@fjnu.edu.cn)

DOI:10.3788/CJL231604

CSTR:32183.14.CJL231604

Topics

laser devices and laser physics

Lasers and Laser Optics

Laser physics

laser manufacturing

Instrumentation, Measurement and Metrology