Forensic Sciences Research, Volume. 10, Issue 1, owae021(2025)

Comprehensive elucidation on the genetic profile of the Hezhou Han population via an efficient InDel panel

Shuyan Mei1,2, Wei Cui3, Man Chen3, Meiming Cai3, Fanzhang Lei3, Xi Wang3, Shangwu Yang4、*, and Bofeng Zhu1,3,5、*
Author Affiliations
  • 1Key Laboratory of Evidence Science (China University of Political Science and Law), Ministry of Education, Beijing, China
  • 2College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang, China
  • 3Guangzhou Key Laboratory of Forensic Multi-Omics for Precision Identification, Department of Forensic Genetics, School of Forensic Medicine, Southern Medical University, Guangzhou, China
  • 4The People's Hospital of Hezhou, Hezhou, China
  • 5Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, China
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    Figures & Tables(6)
    Heatmaps of allelic frequencies and forensic parameters. (A) Insertion allelic frequencies of 57 InDel loci in 31 worldwide populations. (B) Forensic parameters of 57 InDel loci in Hezhou Han population.
    Two phylogenetic trees of 31 different populations. (A) Neighbour-joining tree was performed by MEGA software based on pairwise DA values among 31 populations. (B) Circular phylogenetic tree was constructed by iTOL online software on the basis of pairwise DA values among 31 populations.
    PCA analyses among 31 worldwide populations at population level and individual level. (A) PC1 and PC2 at population level. (B) PC1 and PC3 at population level. (C) PC1 and PC2 at individual level. (D) PC1 and PC3 at individual level.
    The structure analyses (K = 2–4) among 31 populations based on the raw genotyping data of 57 InDel loci.
    Prediction matrix for different intercontinental populations based on 57 autosomal InDel genotyping data. (A) Cross-validation success rates of 4 224 individuals in five intercontinental populations. (B) Cross-validation success rates of 3 388 individuals in three intercontinental populations.
    (A) In values of 57 InDel loci in Hezhou Han population. (B) Cos2 analyses of 57 InDel loci in Hezhou Han population.
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    Shuyan Mei, Wei Cui, Man Chen, Meiming Cai, Fanzhang Lei, Xi Wang, Shangwu Yang, Bofeng Zhu. Comprehensive elucidation on the genetic profile of the Hezhou Han population via an efficient InDel panel[J]. Forensic Sciences Research, 2025, 10(1): owae021

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    Paper Information

    Category: Research Articles

    Received: Jan. 6, 2023

    Accepted: Mar. 27, 2024

    Published Online: Sep. 8, 2025

    The Author Email: Shangwu Yang (1043136026@qq.com), Bofeng Zhu (1043136026@qq.com)

    DOI:10.1093/fsr/owae021

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