Thrombotic disease is a common vascular disease with high mortality and morbidity, it can occur in all blood vessels of the body. The key to diagnosing thrombotic disease lies in thrombus screening, but the formation of thrombus is insidious and unpredictable, so rapid and accurate thrombus screening is crucial in the diagnosis and treatment of thrombotic disease. This review summarizes various thrombus screening and rapid detection methods in recent years, and is expected to provide a reference for the development and clinical application of new thrombus detection methods.