Laser & Optoelectronics Progress, Volume. 60, Issue 7, 0728004(2023)

Graphene Oxide Microfiber-Based Immunosensor for Rabies Virus

Qi Yang1, Binbin Luo1、*, Zhipeng Gu2, Shengxi Wu2, Shenghui Shi1, and Mingfu Zhao1
Author Affiliations
  • 1Chongqing Key Laboratory of Optical Fiber Sensor and Photoelectric Detection, Chongqing University of Technology, Chongqing 400054, China
  • 2Chongqing Key Laboratory of Medicinal Chemistry and Molecular Pharmacology, Chongqing University of Technology, Chongqing 400054, China
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    Figures & Tables(11)
    Schematic diagram of experimental system
    Microscopic image and spectrum of microfiber. (a) Diameter and length of microfiber;(b)interference spectrum of microfiber in water
    RI sensitivity calibration of microfiber. (a) Transmission spectra in different RI solutions;(b)RI sensitivity of microfiber
    Biofunctionalization process of microfiber
    FESEM photos of GO-coated microfiber. (a) 3KX; (b) 30KX
    Energy spectrum of microfiber surface modified with GO
    Spectra detection results in surface modification and functionalization of immunosensor. (a) Spectral evolution of microfiber; (b) corresponding wavelength red shift
    RV antibody detection experiment of immunosensor. (a) Change curves of spectrum with RV antigen concentration; (b) variation curve of resonance wavelength shift with time
    Relationship between wavelength red shift of microfiber immunosensor and concentration of RV antibody. (a) Langmuir curve fitting diagram; (b) detection sensitivity of microfiber immunosensor
    Experimental results of clinical immunodetection of microfiber immunosensors. (a) Evolution curve of spectrum; (b) changes of resonance wavelength shift
    • Table 1. Elemental mass fraction of microfiber surface modified with GO

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      Table 1. Elemental mass fraction of microfiber surface modified with GO

      ChemicalMass fractionAtomic percentage
      Amount100100
      C51.4167.85
      O11.0810.98
      Si37.5121.17
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    Qi Yang, Binbin Luo, Zhipeng Gu, Shengxi Wu, Shenghui Shi, Mingfu Zhao. Graphene Oxide Microfiber-Based Immunosensor for Rabies Virus[J]. Laser & Optoelectronics Progress, 2023, 60(7): 0728004

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    Paper Information

    Category: Remote Sensing and Sensors

    Received: Jan. 21, 2022

    Accepted: Mar. 29, 2022

    Published Online: May. 24, 2023

    The Author Email: Binbin Luo (luobinbin@cqut.edu.cn)

    DOI:10.3788/LOP220600

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