Dual-Modality Endoscopic Probe for Optical Coherence Tomography Imaging and pH Sensing

Wang Jianping; Chen Minghui; Tan Weijie; Feng Yuanyuan; Zheng Gang

doi:10.3788/CJL202047.0907001

Chinese Journal of Lasers, Volume. 47, Issue 9, 907001(2020)

Dual-Modality Endoscopic Probe for Optical Coherence Tomography Imaging and pH Sensing

Wang Jianping, Chen Minghui^*, Tan Weijie, Feng Yuanyuan, and Zheng Gang

Shanghai Institute for Interventional Medical Devices, School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China

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Figures & Tables(8)

Fig. 1. Structure of probe

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Fig. 2. Light transfer model inside the probe

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Fig. 3. Through focus spot diagram

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Fig. 4. System schematic (SMF: single-mode fibre; DCF: double clad fiber; MMF: multimode fiber)

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Fig. 5. Porcine intestine in vitro imaging

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Fig. 6. Calibration curve of SNARF-1 fluorescence intensity ratio versus pH

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Table 1. Fluorescence intensity ratio in the fluorescence emission spectrum across a series of solutions with differing pH values and measured pH values of solution
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Table 1. Fluorescence intensity ratio in the fluorescence emission spectrum across a series of solutions with differing pH values and measured pH values of solution
Actual pH Fluorescence ratio Measured pH
6.4 1.62 6.43
6.6 1.71 6.57
6.8 1.88 6.83
7.0 1.98 6.98
7.2 2.13 7.20
7.4 2.23 7.36
7.6 2.42 7.64

Table 2. Tabel 2 Measured fluorescence intensity ratio
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Table 2. Tabel 2 Measured fluorescence intensity ratio
Measuring
point No. Fluorescence intensity ratio
9:00 13:00 17:00 Average
A 2.28 2.27 2.29 2.28
B 2.29 2.26 2.27 2.27
C 2.27 2.28 2.28 2.28

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Wang Jianping, Chen Minghui, Tan Weijie, Feng Yuanyuan, Zheng Gang. Dual-Modality Endoscopic Probe for Optical Coherence Tomography Imaging and pH Sensing[J]. Chinese Journal of Lasers, 2020, 47(9): 907001

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