Chinese Optics Letters, Volume. 23, Issue 8, 081701(2025)

Structural image-assisted artifact reduction in optical coherence tomography angiography On the Cover

Wenxin Zhang1,2、*, Kangkang Wang1, Hong Zhou1, Jun Pan1, Shiqi Tang1, Ning Liu1、**, Ping Xue2, Jianfei Chen1, Yuchong Lu1, Zhanpeng Hong1, and Mingyu Yang1
Author Affiliations
  • 1College of Electronic and Optical Engineering & College of Flexible Electronics (Future Technology), Nanjing University of Posts and Telecommunications, Nanjing 210023, China
  • 2State Key Laboratory of Low-Dimensional Quantum Physics and Department of Physics, Tsinghua University, Collaborative Innovation Center of Quantum Matter, Beijing 100084, China
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    Figures & Tables(6)
    B-scan structural image and OCTA image: (a) structural image; (b) OCTA image with cmOCT method; (c) step-down exponential filtering method; (d) mean-subtraction method. The scale bar is 100 µm.
    Enhancement of the B-scan structural image: (a) original image; (b) image after depth attenuation compensation; (c) image after Eq. (7); (d) image after Eqs. (6) and (8). The scale bar is 100 µm.
    Cavity image: (a) original cavity image; (b) image after depth attenuation; (c) image after depth attenuation and increasing the difference between cavity and other high-scattering tissues. The scale bar is 100 µm.
    Flowchart of the structural image-assisted artifact reduction method.
    B-scan image and A-line intensity image of the artifact removal method with and without the assistance of the structural image: (a) step-down exponential filtering method; (b) mean-subtraction method; (c) step-down exponential filtering method with the structural image-assisted approach; (d) mean-subtraction method with the structural image-assisted approach; (e) structural image. The scale bar is 100 µm. The noise reference area, located above the vascular region, is marked with a white box for clarity.
    Effect of the structural image-assisted method: (a) en face OCTA image of the palm; (b) x–z projected images of the regions outlined by the gray rectangles in (a); (c) y–z projected images of the regions outlined by the blue rectangles in (a); (d) 3D images of the regions outlined by the green rectangles in (a). The green arrows indicate the vessel signals, while the red arrows point to the artifacts. The scale bar is 100 µm. In (b)–(d), from left to right, the sequence is the step-down exponential filtering method, mean-subtraction method, step-down exponential filtering method with the structural image-assisted approach, and mean-subtraction method with the structural image-assisted approach.
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    Wenxin Zhang, Kangkang Wang, Hong Zhou, Jun Pan, Shiqi Tang, Ning Liu, Ping Xue, Jianfei Chen, Yuchong Lu, Zhanpeng Hong, Mingyu Yang, "Structural image-assisted artifact reduction in optical coherence tomography angiography," Chin. Opt. Lett. 23, 081701 (2025)

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    Paper Information

    Category: Biophotonics

    Received: Jan. 22, 2025

    Accepted: Apr. 3, 2025

    Posted: Apr. 3, 2025

    Published Online: Jul. 23, 2025

    The Author Email: Wenxin Zhang (zhangwx@njupt.edu.cn), Ning Liu (liuning0127@njupt.edu.cn)

    DOI:10.3788/COL202523.081701

    CSTR:32184.14.COL202523.081701

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