Fig. 1. Mathematical model of our photon counting imaging system.

Fig. 2. Pickup stage of photon counting microscopy using SAII.

Fig. 3. Recorded images: (a) original image; (b) photon-limited image with Np=20000.

Fig. 4. Reconstruction results by the following: (a) computational volumetric reconstruction; (b) MLE; (c) MAP with fixed statistical parameters; (d) MAP with adaptive statistical parameters.

Fig. 5. MSE for various reconstruction depths.