International Journal of Cardiovascular Disease, Volume. 52, Issue 4, 249(2025)

Dipteris sinensis (Kudiezi) improves cardiac function in rats with heart failure by regulating mitochondrial apoptosis

WANG Yubing1、*, DU Yana2, XIAO Bin2, GAO Wei3, LIU Yan4, SONG Wenjing5, and SHEN Fengmei1
Author Affiliations
  • 1Department of Traditional Chinese Medicine, Fourth People's Hospital of Hengshui, Hengshui 053000
  • 2Department of General Practice, Fourth People's Hospital of Hengshui, Hengshui 053000
  • 3Department of Internal Medicine, Shijiazhuang Luquan District Traditional Chinese Medicine Hospital, Shijiazhuang 050299
  • 4Department of Cardiology, Yanshan County People's Hospital, Cangzhou 061399
  • 5Department of Cardiology, Fourth People's Hospital of Hengshui, Hengshui 053000, China
  • show less
    References(12)

    [1] [1] Mascolo A, di Mauro G, Cappetta D, et al. Current and future therapeutic perspective in chronic heart failure[J]. Pharmacol Res, 2022, 175: 106035.

    [2] [2] Hinton A Jr, Claypool SM, Neikirk K, et al. Mitochondrial structure and function in human heart failure[J]. Circ Res, 2024, 135(2): 372-396.

    [3] [3] Shi YJ, Zhang Z, Yin QQ, et al. Cardiac-specific overexpression of miR-122 induces mitochondria-dependent cardiomyocyte apoptosis and promotes heart failure by inhibiting Hand2[J]. J Cell Mol Med, 2021, 25(11): 5326-5334.

    [4] [4] Wang HJ, Zhang CW, Li MN, et al. Antimicrobial peptides mediate apoptosis by changing mitochondrial membrane permeability[J]. Int J Mol Sci, 2022, 23(21): 12732.

    [5] [5] Green DR. The mitochondrial pathway of apoptosis: part Ⅰ: MOMP and beyond[J]. Cold Spring Harb Perspect Biol, 2022, 14(5): a041038.

    [9] [9] Huang DJ, Hua W, Fang Q, et al. Biventricular pacemaker and defibrillator implantation in patients with chronic heart failure in China[J]. ESC Heart Fail, 2021, 8(1): 546-554.

    [10] [10] Thandavarayan RA, Chitturi KR, Guha A. Pathophysiology of acute and chronic right heart failure[J]. Cardiol Clin, 2020, 38(2): 149-160.

    [11] [11] Han YD, Cao Y, Han XX, et al. Hyperuricemia and gout increased the risk of long-term mortality in patients with heart failure: insights from the National Health and Nutrition Examination Survey[J]. J Transl Med, 2023, 21(1): 463.

    [12] [12] Zhuang LF, Jia KN, Chen C, et al. DYRK1B-STAT3 drives cardiac hypertrophy and heart failure by impairing mitochondrial bioenergetics[J]. Circulation, 2022, 145(11): 829-846.

    [13] [13] Guan ZJ, Chen J, Wang LH, et al. Nuanxinkang prevents the development of myocardial infarction-induced chronic heart failure by promoting PINK1/Parkin-mediated mitophagy[J]. Phytomedicine, 2023, 108: 154494.

    [14] [14] Lin LW, Xu HL, Yao ZY, et al. Jin-Xin-Kang alleviates heart failure by mitigating mitochondrial dysfunction through the calcineurin/dynamin-related protein 1 signaling pathway[J]. J Ethnopharmacol, 2024, 335: 118685.

    [15] [15] Zhang W, Yuan SL, Qiang JC, et al. Malvidin mitigates sepsis-induced cardiac injury by modulating the TLR4-iNOS-COX-2 inflammatory pathway and the Bax/Bcl-2/Cyto-C mitochondrial apoptosis pathway in a p38 MAPK-dependent manner[J]. Biomed Environ Sci, 2024, 37(2): 221-227.

    Tools

    Get Citation

    Copy Citation Text

    WANG Yubing, DU Yana, XIAO Bin, GAO Wei, LIU Yan, SONG Wenjing, SHEN Fengmei. Dipteris sinensis (Kudiezi) improves cardiac function in rats with heart failure by regulating mitochondrial apoptosis[J]. International Journal of Cardiovascular Disease, 2025, 52(4): 249

    Download Citation

    EndNote(RIS)BibTexPlain Text
    Save article for my favorites
    Paper Information

    Category:

    Received: Nov. 18, 2024

    Accepted: Aug. 25, 2025

    Published Online: Aug. 25, 2025

    The Author Email: WANG Yubing (soufu80127@163.com)

    DOI:10.3969/j.issn.1673-6583.2025.04.011

    Topics