Liquid crystal elastomers (LCEs) have potential applications in medical micro-robotics, controllable surface microstructures, and microfluidics due to their programmable shape morphing and up to 400% strain. To achieve high-resolution molecular orientations and high-precision LCE microstructures, advanced alignment and micro/nano-fabrication techniques are required. Here, we presented current alignment techniques and micro/nano-fabrication techniques for LCE micro-structures, summarized their applications in micro-actuators, artificial muscle fibers, and controllable surfaces, and envisaged their future development in medical micro-robotics.