Laboratory Animal and Comparative Medicine, Volume. 45, Issue 4, 411(2025)

Progress and Evaluation of Animal Model of Heart Qi-Yin Deficiency Syndrome

LIU Yayi1,2, JIA Yunfeng1,2, ZUO Yiming1,2, ZHANG Junping1,2, and LÜ1,2、*
Author Affiliations
  • 1First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
  • 1Shichao
  • 2First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
  • 2National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China
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    References(5)

    [4] [4] LEUNG A Y L, ZHANG J L, CHAN C Y, et al. Validation of evidence-based questionnaire for TCM syndrome differentiation of heart failure and evaluation of expert consensus[J]. Chin Med, 2023, 18(1): 70. DOI: 10.1186/s13020-023-00757-1.

    [30] [30] YANG J, TIAN S S, ZHAO J, et al. Exploring the mechanism of TCM formulae in the treatment of different types of coronary heart disease by network pharmacology and machining learning[J]. Pharmacol Res, 2020, 159: 105034. DOI: 10.1016/j.phrs.2020.105034.

    [31] [31] GUO R, LUO X L, LIU J J, et al. Omics strategies decipher therapeutic discoveries of traditional Chinese medicine against different diseases at multiple layers molecular-level[J]. Pharmacol Res, 2020, 152: 104627. DOI: 10.1016/j.phrs.2020.104627.

    [35] [35] JIANG Y, ZHAO Q, HUANG S M, et al. Identification and comparison of potential biomarkers by proteomic analysis in traditional Chinese medicine-based heart failure syndromes[J]. Evid Based Complement Alternat Med, 2022, 2022: 6338508. DOI: 10.1155/2022/6338508.

    [38] [38] CHAI C Z, KOU J P, ZHU D N, et al. Mice exposed to chronic intermittent hypoxia simulate clinical features of deficiency of both qi and Yin syndrome in traditional Chinese medicine[J]. Evid Based Complement Alternat Med, 2011, 2011: 356252. DOI: 10.1093/ecam/nep226.

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    LIU Yayi, JIA Yunfeng, ZUO Yiming, ZHANG Junping, LÜ. Progress and Evaluation of Animal Model of Heart Qi-Yin Deficiency Syndrome[J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 411

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    Paper Information

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    Received: Nov. 22, 2024

    Accepted: Sep. 10, 2025

    Published Online: Sep. 10, 2025

    The Author Email: L&#220 (372272027@qq.com)

    DOI:10.12300/j.issn.1674-5817.2024.176

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