Fig. 1. Schematic of large-FOV optical diffraction tomography microscopy. (a) Schematic of imaging system; (b) structure of D-shaped mirror

Fig. 2. Schematic of traditional system and large-FOV system imaging in complex biological samples. (a) Normal cell imaging by large-FOV system; (b) normal cell imaging by traditional ODT system; (c) giant cell imaging by large-FOV system; (d) giant cell imaging by traditional ODT system

Fig. 3. Reconstruction results of 5 μm polystyrene microspheres at different imaging depths in large-FOV and traditional ODT systems. (a) Recovery results of 5 μm polystyrene microspheres in large-FOV system; (b) magnification of polystyrene microsphere imaging results at different defocusing depths for area in red square in (a); (c) recovery results in traditional system corresponding to (b)

Fig. 4. Comparison of image SNR between large-FOV and traditional ODT systems

Fig. 5. Reconstruction results of living Hela cells at different imaging depths in large-FOV and traditional ODT systems. (a) Recovery results of Hela cells in large-FOV system; (b) magnification of living Hela cell imaging results at different defocusing depths for red square area in (a); (c) results in traditional system corresponding to (b)

Fig. 6. Reconstruction results of living Hela cells at different time points in large-FOV system. (a) 94:00; (b) 96:00; (c) 97:00; (d) 99:00

Fig. 7. Reconstruction results of the cell in yellow ellipse area in Fig. 6 at different time points in large-FOV system