Ultrashort pulsed lasers operating in the deep ultraviolet (UV) spectrum, with high energy and peak power, are crucial for a wide range of advanced applications. In this study, we successfully developed a high-power, mode-locked Nd∶YVO₄ laser operating at 1064 nm, achieving an average output power of 9.32 W, a pulse repetition rate of 78.12 MHz, and a pulse width of 13.9 ps. The 1064 nm picosecond laser was subsequently used as a seed in a regenerative amplifier, where a stable pulsed laser was obtained at 200 kHz with a maximum average output power of 26.7 W and a pulse width of 16.3 ps. Furthermore, we generated a green laser at 532 nm and a deep UV laser at 266 nm through two stages of nonlinear frequency doubling. The green laser exhibited an average output power of 14.24 W and a pulse width of 12.6 ps, whereas the deep UV laser achieved an output power of 3.94 W and a pulse width of approximately 14.3 ps. The 266 nm laser delivered a single pulse energy of 19.7 μJ and a peak power of 1.37 MW.