International Journal of Digestive Diseases, Volume. 45, Issue 3, 159(2025)

Expression and clinical value of serum lncRNA OTUD6B-AS1 and lncRNA ITGB8-AS1 in patients with colorectal cancer

REN Xianlin1, WANG Jinjie2, ZHANG Ying3, and LIN Qiuju4、*
Author Affiliations
  • 1First Department of Gastroenterology, Rehabilitation University Qingdao Central Hospital, Qingdao 266013, China
  • 2Department of Medical Engineering, Rehabilitation University Qingdao Central Hospital, Qingdao 266013, China
  • 3Department of Obstetrical, Rehabilitation University Qingdao Central Hospital, Qingdao 266013, China
  • 4Second Department of Oncology, Rehabilitation University Qingdao Central Hospital, Qingdao 266013, China
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    References(9)

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    [13] [13] Jung G, Hernndez-Illn E, Moreira L, et al. Epigenetics of colorectal cancer: biomarker and therapeutic potential[J]. Nat Rev Gastroenterol Hepatol, 2020, 17(2): 111-130.

    [14] [14] Fang D, Ou X, Sun K, et al. m6A modification-mediated lncRNA TP53TG1 inhibits gastric cancer progression by regulating CIP2A stability[J]. Cancer Sci, 2022, 113(12): 4135-4150.

    [16] [16] Cai Y, Li Y, Shi C, et al. LncRNA OTUD6B-AS1 inhibits many cellular processes in colorectal cancer by sponging miR-21-5p and regulating PNRC2[J]. Hum Exp Toxicol, 2021, 40(9): 1463-1473.

    [18] [18] Lin X, Zhuang S, Chen X, et al. lncRNA ITGB8-AS1 functions as a ceRNA to promote colorectal cancer growth and migration through integrin-mediated focal adhesion signaling[J]. Mol Ther, 2022, 30(2): 688-702.

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    REN Xianlin, WANG Jinjie, ZHANG Ying, LIN Qiuju. Expression and clinical value of serum lncRNA OTUD6B-AS1 and lncRNA ITGB8-AS1 in patients with colorectal cancer[J]. International Journal of Digestive Diseases, 2025, 45(3): 159

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    Paper Information

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    Received: Aug. 8, 2024

    Accepted: Aug. 25, 2025

    Published Online: Aug. 25, 2025

    The Author Email: LIN Qiuju (w20kwq@163.com)

    DOI:10.3969/j.issn.1673-534x.2025.03.006

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