Acta Laser Biology Sinica, Volume. 33, Issue 4, 326(2024)

The Protective Effect of Umbilical Cord Mesenchymal Stem Cell Exosomes on Acute Lung Injury in Neonatal Rats

LONG Jing1,2, MAO Ying2, YAN Feng1, LIU Ailong1, DING Hao1, CHEN Anji3, HU Xiang2、*, and YOU Changqiao1
Author Affiliations
  • 1Hunan Provincial Engineering Technology Research Center of Stem Cell Exosome, Hunan Landfar Biotechnology Co. Ltd., Changsha 410027, China
  • 2College of Life Sciences, Hunan Normal University, Changsha 410081, China
  • 3Changsha Hospital for Maternal & Child Health Care Affiliated to Hunan Normal University, Changsha 410007, China
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    References(20)

    [1] [1] MATTHAY M A, ZIMMERMAN G A, ESMON C, et al. Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group[J]. American Journal of Respiratory and Critical Care Medicine, 2003, 167(7): 1027-1035.

    [2] [2] MEYER N J, GATTINONI L, CALFEE C S. Acute respiratory distress syndrome[J]. Lancet, 2021, 398(10300): 622-637.

    [3] [3] HERRIDGE M S, TANSEY C M, MATT A, et al. Functional disability 5 years after acute respiratory distress syndrome[J]. The New England Journal Medicine, 2011, 364(14): 1293-1304.

    [4] [4] RUBENFELD G D, CALDWELL E, PEABODY E, et al. Incidence and outcomes of acute lung injury[J]. The New England Journal Medicine, 2005, 353(16): 1685-1693.

    [5] [5] LU Q Y, YU S F, MENG X Y, et al. MicroRNAs: important regulatory molecules in acute lung injury/acute respiratory distress syndrome[J]. International Journal of Molecular Sciences, 2022, 23(10): 5545-5575.

    [6] [6] ZHANG J, LI S, LI L, et al. Exosome and exosomal microRNA: trafficking, sorting, and function[J]. Genomics Proteomics Bioinformatics, 2015, 13(1): 17-24.

    [7] [7] PARK J, KIM S, LIM H, et al. Therapeutic effects of human mesenchymal stem cell microvesicles in an ex vivo perfused human lung injured with severe E. coli pneumonia[J]. Thorax, 2019, 74(1): 43-50.

    [8] [8] MEYER N J, GATTINONI L, CALFEE C S. Acute respiratory distress syndrome[J]. Lancet, 2021, 398(10300): 622-637.

    [9] [9] CHEN H I, KAO S J, WANG D, et al. Acute respiratory distress syndrome[J]. Journal of Biomedical Science, 2003, 10(6 Pt 1): 588-592.

    [10] [10] THOMPSON B T, CHAMBERS R C, LIU K D. Acute respiratory distress syndrome[J]. The New England Journal Medicine, 2017, 377(6): 562-572.

    [11] [11] HU Y, WANG J, ZHOU Y, et al. Peptidomics analysis of umbilical cord blood reveals potential preclinical biomarkers for neonatal respiratory distress syndrome[J]. Life Science, 2019, 236: 116737-116743.

    [12] [12] DING D C, SHYU W C, LIN S Z. Mesenchymal stem cells[J]. Cell Transplant, 2011, 20(1): 5-14.

    [13] [13] UCCELLI A, MORETTA L, PISTOIA V. Mesenchymal stem cells in health and disease[J]. Nature Reviews Immunology, 2008, 8(9): 726-736.

    [14] [14] SAMSONRAJ R M, RAGHUNATH M, NURCOMBE V, et al. Concise review: multifaceted characterization of human mesenchymal stem cells for use in regenerative medicine[J]. Stem Cells Translational Medicine, 2017, 6(12): 2173-2185.

    [15] [15] SPEER C P. Neonatal respiratory distress syndrome: an inflammatory disease?[J]. Neonatology, 2011, 99(4): 316-319.

    [16] [16] WORTZEL I, DROR S, KENIFIC C M, et al. Exosome-mediated metastasis: communication from a distance[J]. Developmental Cell, 2019, 49(3): 347-360.

    [17] [17] ABBASZADEH H, GHORBANI F, DERAKHSHANI M, et al. Human umbilical cord mesenchymal stem cell-derived extracellular vesicles: a novel therapeutic paradigm[J]. Journal of Cellular Physiology, 2020, 235(2): 706-717.

    [18] [18] SU C F, KAO S J, CHEN H I. et al. Acute respiratory distress syndrome and lung injury: pathogenetic mechanism and therapeutic implication[J]. World Journal of Critical Care Medicine, 2012, 1(2): 50-60.

    [19] [19] LIU C, XIAO K, XIE L X. Advances in mesenchymal stromal cell therapy for acute lung injury/acute respiratory distress syndrome[J]. Frontiers in Cell and Developmental Biology, 2022, 10: 951764-951781.

    [20] [20] GURUNATHAN S, KANG M H, KIM J H. A comprehensive review on factors influences biogenesis, functions, therapeutic and clinical implications of exosomes[J]. International Journal of Nanomedicine, 2021, 16: 1281-1312.

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    LONG Jing, MAO Ying, YAN Feng, LIU Ailong, DING Hao, CHEN Anji, HU Xiang, YOU Changqiao. The Protective Effect of Umbilical Cord Mesenchymal Stem Cell Exosomes on Acute Lung Injury in Neonatal Rats[J]. Acta Laser Biology Sinica, 2024, 33(4): 326

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    Paper Information

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    Received: Jan. 5, 2024

    Accepted: Dec. 20, 2024

    Published Online: Dec. 20, 2024

    The Author Email: Xiang HU (huxiang@hunnu.edu.cn)

    DOI:10.3969/j.issn.1007-7146.2024.04.005

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