Laser & Optoelectronics Progress, Volume. 62, Issue 14, 1417003(2025)

Low-Dose Computed Tomography Image Denoising Method Based on Cross Domain and High Receptive Field

Lu Zhang1、*, Pengju Liu2,3, and Shigang Liu4
Author Affiliations
  • 1Digital Campus Construction Center, Chang'an University, Xi'an 710064, Shaanxi , China
  • 2School of Medicine and Health, Harbin Institute of Technology, Harbin 150001, Heilongjiang , China
  • 3Zhengzhou Research Institute, Harbin Institute of Technology, Zhengzhou 450000, Henan , China
  • 4School of Computer Science, Shaanxi Normal University, Xi'an 710119, Shaanxi , China
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    Figures & Tables(15)
    The sub-band images of dual-tree complex wavelet
    The architecture of three-level LDTNet
    The average PSNR curves of different LDTNet
    The average PSNR curve of structure 4
    The average PSNR curve of structure 8
    The average PSNR curve of structure 12
    The comparison of denoised images on AAPM-1 mm-L109-173
    The comparison of denoised images on AAPM-3 mm-L109-33
    • Table 1. The parameters of denoising network

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      Table 1. The parameters of denoising network

      Denoising networkDilation factorReceptive fieldKernel size
      Total receptive field59
      Dilated convolution+ReLU 1133×3×128
      Dilated convolution+ReLU 2253×3×128
      Dilated convolution+ReLU 3373×3×128
      Dilated convolution+ReLU 4493×3×128
      Dilated convolution+ReLU 55113×3×128
      Dilated convolution+ReLU 6493×3×128
      Dilated convolution+ReLU 7373×3×128
      Dilated convolution+ReLU 8253×3×128
      Dilated convolution+ReLU 9133×3×128
    • Table 2. The number of CT slices from 10 patients in the AAPM dataset

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      Table 2. The number of CT slices from 10 patients in the AAPM dataset

      Patient ID1 mm slice3 mm slice
      Total59362378
      L067560224
      L096823330
      L109318128
      L143585234
      L192600240
      L286525210
      L291856343
      L310533214
      L333610244
      L506526211
    • Table 3. Comparison of LDTNet with different structures

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      Table 3. Comparison of LDTNet with different structures

      Structure No.DTCWTNetwork structureReceptive fieldModel size /MBPSNR /dB
      1One-levelJ0-Net+J1-Net59×29.628.7504
      2One-levelJ0-Net+J1-Net+X59×29.628.7538
      3One-levelJ0-Net+J1-Net+X-Net59×214.428.7805
      4One-levelJ0-Net+J1-Net+X-Net+X59×214.428.7820
      5Two-levelJ0-Net+J1-Net+J2-Net59×314.428.6849
      6Two-levelJ0-Net+J1-Net+J2-Net+X59×314.428.6889
      7Two-levelJ0-Net+J1-Net+J2-Net+X-Net59×319.228.7818
      8Two-levelJ0-Net+J1-Net+J2-Net+X-Net+X59×319.228.7862
      9Three-levelJ0-Net+J1-Net+J2-Net+J3-Net59×419.228.6113
      10Three-levelJ0-Net+J1-Net+J2-Net+J3-Net+X59×419.228.6166
      11Three-levelJ0-Net+J1-Net+J2-Net+J3-Net+X-Net59×425.028.7839
      12Three-levelJ0-Net+J1-Net+J2-Net+J3-Net+X-Net+X59×425.028.7892
    • Table 4. The comparison of average PSNR for different filter combinations

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      Table 4. The comparison of average PSNR for different filter combinations

      FilterNear Symmetric ANear Symmetric B
      Qshift 0628.737528.7770
      Qshift A28.763828.7785
      Qshift B28.767028.7892
      Qshift C28.786728.7685
      Qshift D28.778728.7755
      FilterAntoniniLeGall
      Qshift 0628.768328.7712
      Qshift A28.760628.7785
      Qshift B28.781628.7601
      Qshift C28.780928.7723
      Qshift D28.775228.7880
    • Table 5. The comparison of average PSNR and SSIM for different methods on AAPM-1 mm dataset

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      Table 5. The comparison of average PSNR and SSIM for different methods on AAPM-1 mm dataset

      MethodPSNR /dBSSIM
      LDCT18.85040.6125
      CNN1024.6883 ± 0.50660.6655 ± 0.0128
      AAPM-Net24.7552 ± 0.55430.6719 ± 0.0133
      RED-CNN24.7671 ± 0.56810.6723 ± 0.0151
      DRN-LDCT24.8241 ± 0.52030.6733 ± 0.0149
      MDTNet24.8650 ± 0.53390.6749 ± 0.0130
      LDTNet24.8859 ± 0.51020.6760 ± 0.0135
    • Table 6. The comparison of average PSNR and SSIM for different methods on AAPM-3 mm dataset

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      Table 6. The comparison of average PSNR and SSIM for different methods on AAPM-3 mm dataset

      MethodPSNR /dBSSIM
      LDCT22.93380.6732
      CNN1028.6361 ± 0.55100.7478 ± 0.0012
      AAPM-Net28.6553 ± 0.57770.7480 ± 0.0099
      RED-CNN28.7254 ± 0.58110.7512 ± 0.0153
      DRN-LDCT28.7284 ± 0.56020.7496 ± 0.0125
      MDTNet28.7555 ± 0.56740.7517 ± 0.0110
      LDTNet28.7892 ± 0.55450.7633 ± 0.0095
    • Table 7. Comparison of different methods

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      Table 7. Comparison of different methods

      MethodModel size /MBTotal time /sAverage time /s
      MDTNet16.03.850.193
      DRN-LDCT23.95.010.251
      LDTNet25.05.250.263
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    Lu Zhang, Pengju Liu, Shigang Liu. Low-Dose Computed Tomography Image Denoising Method Based on Cross Domain and High Receptive Field[J]. Laser & Optoelectronics Progress, 2025, 62(14): 1417003

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    Paper Information

    Category: Medical Optics and Biotechnology

    Received: Nov. 27, 2024

    Accepted: Feb. 21, 2025

    Published Online: Jul. 16, 2025

    The Author Email: Lu Zhang (zlu@chd.edu.cn)

    DOI:10.3788/LOP242328

    CSTR:32186.14.LOP242328

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