Chinese Journal of Lasers, Volume. 45, Issue 6, 0607004(2018)

Blood Flow Measurementwith Photoacoustic Microscopy and Optical Coherence Tomography

Liuhua Pan1,2, Xiangyang Zhang3, Zhongliang Li1,2, Nan Nan1, Yang Bu1,2, Yan Chen1,2, Xuan Wang1,2, and Xiangzhao Wang1,2、*
Author Affiliations
  • 1 Laboratory of Information Optics and Optoelectronic Technology, Shanghai Institute of Optics and Fine Mechanics,Chinese Academy of Sciences, Shanghai 201800, China
  • 2 University of Chinese Academy of Sciences, Beijing 100049, China
  • 3 School of Science, Jiangnan University, Wuxi, Jiangsu 214122, China
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    Figures & Tables(6)
    Schematic of blood passing through probe beam
    Schematic of single red blood cell passing through the vessel and probe beam
    Schematic of PA/OCT experimental system
    Blood flow velocity measured by PAM. (a) Image of blood in the vessel; (b) normalized P(t) signal;(c) calculated autocorrelation correlation function and fitted curves of P(t); (d) ratio of flow velocity measured by PAM to original flow velocity at different tilt angles
    Blood flow velocity measured by OCT. (a) Cross section image of vessel with blood; (b) B-scan image obtained by continuous A-line signal acquisition at the same position; (c) blood flow velocity profile in the vessel; (d) ratio of flow velocity measured by OCT to original flow velocity at different tilt angles
    • Table 1. Blood flow velocity measured by PA/OCT

      View table

      Table 1. Blood flow velocity measured by PA/OCT

      Designedvelocity /(mm·s-1)1
      Designed angle /(°)015304560
      Measured velocityby PAM /(mm·s-1)1.0000.9590.8930.7060.500
      Measured velocityby OCT /(mm·s-1)00.3000.4960.6560.887
      Measuredvelocity /(mm·s-1)1.0001.0051.0220.9641.018
      Measured angle /(°)017.329.142.960.6
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    Liuhua Pan, Xiangyang Zhang, Zhongliang Li, Nan Nan, Yang Bu, Yan Chen, Xuan Wang, Xiangzhao Wang. Blood Flow Measurementwith Photoacoustic Microscopy and Optical Coherence Tomography[J]. Chinese Journal of Lasers, 2018, 45(6): 0607004

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    Paper Information

    Category: biomedical photonics and laser medicine

    Received: Jan. 3, 2018

    Accepted: --

    Published Online: Jul. 5, 2018

    The Author Email: Xiangzhao Wang (waz26267@siom.ac.cn)

    DOI:10.3788/CJL201845.0607004

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