Chinese Journal of Lasers, Volume. 50, Issue 9, 0907206(2023)
Mechanism of Pain in Photodynamic Therapy and Clinical Interventions
Figures & Tables(4)
Table 1. Intervention means and effects of relieving pain during PDT treatment
View tableTable 1. Intervention means and effects of relieving pain during PDT treatment
Intervention means Disease Drug or measure taken for relieving pain Pain-relieving effect Ref. Oral drugs Actinic keratosis，Bowens disease，superficial basal cell carcinoma Paracetamol，aminophenol codeine，ibuprofen No obvious effect ［ 74 -75 ］Intravenous injection Port-wine stain Flurbiprofen Effective ［ 76 ］Actinic keratosis Piritramide No obvious effect ［ 79 ］Subcutaneous infiltration anesthesia Actinic keratosis Ringer’s solution，ropivacaine，
prilocaine，epinephrine
Effective ［ 77 ］Scalp nerve block Actinic keratosis Ropivacaine Effective ［ 79 ］Facial coating Actinic keratosis Morphine gel No obvious effect ［ 80 ］Port-wine stain Lidocaine cream No obvious effect ［ 81 ］Actinic keratosis，Bowens disease，superficial basal cell carcinoma Tetracaine gel No obvious effect ［ 82 ］Drug/water spray Actinic keratosis Chamomile and menthol Effective ［ 83 ］Inhalation Lichen sclerosus Mixture of N2O（volume fraction of 50%）and O2 （volume fraction of 50%） Effective ［ 84 -85 ］Cold air Hypertrichosis，port-wine stains，hemangioma，essential telangiectasias，superficial skin cancers，basal cell carcinomas，actinic keratosis - Effective ［ 45 ，86 -88 ］Adjusting light wavelength Actinic keratosis Changing green light to red light Effective ［ 89 ］Adjusting irradiance Actinic keratosis，
basal cell carcinomas
Reducing irradiance Effective ［ 91 ，93 ，94 ］Sun-PDT Actinic keratosis - Effective ［ 96 ］
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Dongqin Lei, Jing Liu, Zhenxi Zhang, Weihui Zeng, Cuiping Yao. Mechanism of Pain in Photodynamic Therapy and Clinical Interventions[J]. Chinese Journal of Lasers, 2023, 50(9): 0907206
Paper Information
Category: Optical Diagnostics and Therapy
Received: Nov. 3, 2022
Accepted: Jan. 3, 2023
Published Online: Apr. 24, 2023
The Author Email: Zeng Weihui (zengwh88@126.com), Yao Cuiping (zsycp@xjtu.edu.cn)
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