Spatially Resolved Reflectance in Sub-Diffusive Regime Measurement System for Mucosal Lesion Recognition

Qi Zhang; Limin Zhang; Jiayu Wang; Jingyi An; Jing Wang; chen Chen; Feng Gao

doi:10.3788/CJL202148.2007001

Chinese Journal of Lasers, Volume. 48, Issue 20, 2007001(2021)

Spatially Resolved Reflectance in Sub-Diffusive Regime Measurement System for Mucosal Lesion Recognition

Qi Zhang¹, Limin Zhang^1,2、*, Jiayu Wang¹, Jingyi An¹, Jing Wang³, chen Chen³, and Feng Gao^1,2

Author Affiliations

¹College of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China

²Tianjin Key Laboratory of Biomedical Detecting Techniques and Instruments, Tianjin 300072, China

³The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, China

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Figures & Tables(9)

Fig. 1. Schematic of experimental system

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Fig. 2. System stability measurement results

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Fig. 3. Experimental multi-frequency crosstalk ratio

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Fig. 4. Intensity amplitude measured at different ambient light intensities. (a) Without digital lock-in; (b) digital lock-in

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Fig. 5. Linearity assessments of the system at source-detector separation of 220 μm

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Fig. 6. Optical parameter inversion results. (a) μ_a; (b) μ'_s; (c)γ

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Table 1. Correlation coefficient of linear fitting at four wavelengths
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Table 1. Correlation coefficient of linear fitting at four wavelengths
Wavelength /nm Source-dectetor separation /μm
220 440 660 880 1100
520 0.9992 0.9982 0.9977 0.9987 0.9984
650 0.9991 0.9994 0.9994 0.9992 0.9992
785 0.9988 0.9989 0.9991 0.9973 0.9985
830 0.9985 0.9993 0.9985 0.9988 0.9983

Table 2. Optical parameters of turbid phantoms

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Table 2. Optical parameters of turbid phantoms

No.	μ_a /cm^-1	μ'_s /cm^-1	γ	No.	μ_a /cm^-1	μ'_s /cm^-1	γ
P1	0.001	9	2.2507	P7	0.5	13	2.0110
P2	0.001	13	2.0110	P8	0.1	17	1.9992
P3	0.001	17	1.9992	P9	0.5	17	1.9992
P4	0.001	29	2.0110	P10	1.5	17	1.9992
P5	0.1	9	2.2507	P11	0.1	29	2.0110
P6	2.0	9	2.2507	P12	2.0	29	2.0110

Table 3. Root-mean-square error and relative root-mean-square error of optical parameters
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Table 3. Root-mean-square error and relative root-mean-square error of optical parameters
Parameter Root-mean-square error Relative root-mean-square error /%
μ_a 0.1023 26.0074
μ'_s 0.5442 2.9835
γ 0.0393 1.9139

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Qi Zhang, Limin Zhang, Jiayu Wang, Jingyi An, Jing Wang, chen Chen, Feng Gao. Spatially Resolved Reflectance in Sub-Diffusive Regime Measurement System for Mucosal Lesion Recognition[J]. Chinese Journal of Lasers, 2021, 48(20): 2007001

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