Laser & Optoelectronics Progress, Volume. 55, Issue 11, 111701(2018)

Effect of Various Neonatal Jaundice Therapeutic Light Sources in Degradation of Bilirubin in Vitro Blood

Jianing Zhang1, Zhenning Guo1、*, Jieben Lin2, Jianpeng Li1, Zhonghang Chen1, and Dongdong Xue1
Author Affiliations
  • 1 Fujian Key Laboratory of Optical Beam Transmission and Transformation, College of Information Science and Engineering, Huaqiao University, Xiamen, Fujian 361021, China
  • 2 Fujian Quanzhou Sigo LED Lighting Technology Co., Ltd., Quazhou, Fujian 362302, China
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    Figures & Tables(11)
    Absorption spectrum of the bilirubin in extracorporeal blood
    Photo-electric measurements system. (a) YF1000 light-color electricity integrated system; (b) ATA-500/1000 auto-temperature photoelectric analysis and measurement system
    Relative spectral power distributions of monochromatic LEDs with different peak wavelengths
    Matching figure of fitting spectrum
    Pictures. (a) Arrangement of LED lamps on Al substrate (b) manufactured light source in jaundice therapeutic device
    Luminescence spectrum of manufactured light source in jaundice therapeutic device and the absorption spectrum of the bilirubin in extracorporeal blood
    Luminescence spectra of four light sources and the absorption spectrum of the extracorporeal bilirubin
    Change of concentration of bilirubin solution with irradiation time
    • Table 1. Photoelectric parameters of four kinds of LEDs

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      Table 1. Photoelectric parameters of four kinds of LEDs

      EmittingcolorPeakwavelength /nmFWHM /nmForwardcurrent /mAForwardvoltage /VLuminousflux /lm
      Lake blue44521.320-303.0-3.21.1-1.5
      Blue46522.620-303.0-3.22.2-2.5
      Blue47520.020-303.0-3.22.0-3.2
      Blue-green49529.320-303.0-3.26.9-7.1
    • Table 2. Concentration of the bilirubin solution after irradiationμmol/L

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      Table 2. Concentration of the bilirubin solution after irradiationμmol/L

      LightsourcePhototherapy time /h
      1248
      A2.6842.1461.7711.299
      B3.4312.4592.4691.229
      C5.4293.8652.4441.521
      D39.13124.06317.4996.526
    • Table 3. Effects of each light source on degradation rate of the bilirubin%

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      Table 3. Effects of each light source on degradation rate of the bilirubin%

      LightsourcePhototherapy time /h
      1248
      A97.9598.3698.6599.01
      B97.3898.1298.1199.06
      C95.8597.0598.1398.84
      D70.1181.6286.6495.02
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    Jianing Zhang, Zhenning Guo, Jieben Lin, Jianpeng Li, Zhonghang Chen, Dongdong Xue. Effect of Various Neonatal Jaundice Therapeutic Light Sources in Degradation of Bilirubin in Vitro Blood[J]. Laser & Optoelectronics Progress, 2018, 55(11): 111701

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    Paper Information

    Category: Medical Optics and Biotechnology

    Received: Mar. 23, 2018

    Accepted: May. 29, 2018

    Published Online: Aug. 14, 2019

    The Author Email: Zhenning Guo (znguo@hqu.edu.cn)

    DOI:10.3788/LOP55.111701

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