[1] [1] ZHANG H X, ZHANG Y, YIN H. Genome editing with mRNA encoding ZFN, TALEN, and Cas9[J]. Molecular Therapy, 2019, 27(4): 735-746.

[2] [2] KIMMEL C B, MILLER C T, KRUZE G,et al.The shaping of pharyngeal cartilages during early development of the zebrafish[J]. Developmental Biology, 1998, 203(2): 245-263.

[3] [3] BOXTEL A L V, KAMSTRA J H, FLUITSMA D M,et al.Dithiocarbamates are teratogenic to developing zebrafish through inhibition of lysyl oxidase activity[J]. Toxicology and Applied Pharmacology, 2010, 244(2): 156-161.

[4] [4] MCMAHON A P, CHAMPION J E, MCMAHON J A,et al.Developmental expression of the putative transcription factor Egr-1 suggests that Egr-1 and c-fos are coregulated in some tissues[J]. Development (Cambridge, England), 1990, 108(2): 281-287.

[5] [5] CHRISTY B A, LAU L F, NATHANS D. A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with “zinc finger” sequences[J]. Proceedings of the National Academy of Sciences, 1988, 85(21): 7857-7861.

[6] [6] LEE S L, SADOVSKY Y, SWIRNOFF A H,et al.Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)[J]. Science, 1996, 273(5279): 1219-1221.

[7] [7] KRISHNARAJU K, NGUYEN H Q, LIEBERMANN D A,et al.The zinc finger transcription factor Egr-1 potentiates macrophage differentiation of hematopoietic cells[J]. Molecular and Cellular Biology, 1995, 15(10): 5499-5507.

[8] [8] WANG Y, HE Y, DONG W,et al.DDIT3 aggravates pulpitis by modulating M1 polarization through EGR1 in macrophages[J]. International Immunopharmacology, 2023, 120(1567/5769): 11.

[9] [9] LEMAIRE P, REVELANT O, BRAVO R,et al.Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells[J]. Proceedings of the National Academy of Sciences, 1988, 85(13): 4691-4695.

[10] [10] LI L C, AMERI A H, WANG S M,et al.EGR1 regulates angiogenic and osteoclastogenic factors in prostate cancer and promotes metastasis[J]. Oncogene, 2019, 38(35): 6241-6255.

[11] [11] PARK K J, MYUNG E, PARK Y L,et al.Expression of early growth response-1 in human gastric cancer and its relationship with tumor cell behaviors and prognosis[J]. Journal of Gastroenterology and Hepatology, 2012, 209(11): 692-699.

[12] [12] HICKS H M, POZDEYEV N, SAMS S B,et al.Fibronectin contributes to a BRAF inhibitor-driven invasive phenotype in thyroid cancer through EGR1, which can be blocked by inhibition of ERK1/2[J]. Molecular Cancer Research, 2023, 21(9): 867-880.

[13] [13] LIN X, JIN Z, LI S,et al.Preliminary study on expression and function of the chicken W chromosome geneMIER3in embryonic gonads[J]. International Journal of Molecular Sciences, 2023, 24(10): 18.

[14] [14] HE J H, YANG X H, ZHANG C N,et al.CNN2 silencing inhibits colorectal cancer development through promoting ubiquitination of EGR1[J]. Life Science Alliance, 2023, 6(8): 13.

[15] [15] GUO Y, MIAO X L, SUN X Y,et al.Zinc finger transcription factor Egf1 promotes non-alcoholic fatty liver disease[J]. JHEP Reports, 2023, 5(6): 15.

[16] [16] DAVIES J P, KUMAR S, SASTRY-DENT L. Use of zinc-finger nucleases for crop improvement[J]. Gene Editing in Plants, 2017, 149(1): 47-63.

[17] [17] BEDELL V M, WANG Y, CAMPBELL J M,et al. In vivogenome editing using a high-efficiency TALEN system[J]. Nature, 2012, 491(7422): 114-118.

[19] [19] LONG F X, ORNITZ D M. Development of the endochondral skeleton[J]. Cold Spring Harbor Perspectives in Biology, 2013, 5(1): a008334.

[20] [20] WIXON J, KELL D. The Kyoto encyclopedia of genes and genomes — KEGG[J]. Yeast, 2000, 1(1): 48-55.

[21] [21] CHEN Z J, YUE S X, ZHOU G,et al.ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation[J]. Journal of Bone and Mineral Research, 2015, 30(5): 765-774.

[22] [22] BUSSE B, GALLOWAY J L, GRAY R S,et al.Zebrafish: an emerging model for orthopedic research[J]. Journal of Orthopaedic Research, 2019, 38(5): 925-936.