Chinese Journal of Lasers, Volume. 50, Issue 21, 2107108(2023)

Ultrawide-Angle Confocal Laser Line Scanning Fundus Imaging

Xingyu Liu1,2, Yun Xiao2,5, Lin Ji1,2, Yulong Liu3, Tongda Wei2,4, and Yunhai Zhang1,2、*
Author Affiliations
  • 1Division of Life Sciences and Medicine, School of Biomedical Engineering (Suzhou), University of Science and Technology of China, Hefei 230026, Anhui, China
  • 2Jiangsu Key Laboratory of Medical Optics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, Jiangsu, China
  • 3The Second Affiliated Hospital, Soochow University, Suzhou 215004, Jiangsu, China
  • 4Jinan Guoke Medical Technology Development Co., Ltd., Jinan 250102, Shandong, China
  • 5Shenyang Guoke Medical Technology Development Co., Ltd., Shenyang 110167, Liaoning, China
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    Figures & Tables(13)
    Optical diagram of system
    Calculation diagram of field of view
    Calculation diagram of aperture
    Computation diagrams. (a) Top view; (b) side view
    Zemax design drawing of detection optical path
    Image quality evaluation charts of detection optical path. (a) Modulation transfer function images; (b) spot diagram
    Experimental system
    Measurement of field of view. (a) Measurement principle; (b) location marking of convergence point; (c) measurement process demonstration
    Measurement of resolution. (a) Imaging of resolution board; (b) strength curve of fourth pair of wires in group 7
    Simulation imaging experiment results. (a) Ultra-wide angle imaging image; (b) normal fundus camera imaging image; (c) high resolution imaging image; (d)‒(f) light intensity curves corresponding to imaging regions
    • Table 1. Designed parameters of each lens

      View table

      Table 1. Designed parameters of each lens

      Lens

      Field of view

      (ultra-wide angle/high resolution)

      Focal length /mm

      Clear aperture

      (ultra-wide angle/high resolution)

      Scanning lens(L314.6°/14.2°70 mm21.8 mm/21.4 mm
      Illuminated lens(L414.6°/14.2°50 mm16.7 mm/16.5 mm
      Imaging objective lens(L514.6°/14.2°50 mm16.7 mm/16.5 mm
      Imaging objective lens(L614.6°/14.2°50 mm16.7 mm/16.5 mm
    • Table 2. Main indicators of TS8203 scanning galvanometer

      View table

      Table 2. Main indicators of TS8203 scanning galvanometer

      ParameterValue
      Mechanical rotation angle±12°
      Small angle response time200 ms
      Linearity99%
      Short range repeatable accuracy15 mrad
      Mirror diameter7 mm
    • Table 3. Actual field of view of system under ultra-wide angle imaging mode

      View table

      Table 3. Actual field of view of system under ultra-wide angle imaging mode

      No.H /mmL /mmθv /(°)θe  /(°)
      1265593.2136.7
      26513793.0136.4
      310020892.5135.7
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    Xingyu Liu, Yun Xiao, Lin Ji, Yulong Liu, Tongda Wei, Yunhai Zhang. Ultrawide-Angle Confocal Laser Line Scanning Fundus Imaging[J]. Chinese Journal of Lasers, 2023, 50(21): 2107108

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    Paper Information

    Category: Biomedical Optical Imaging

    Received: Jun. 21, 2023

    Accepted: Sep. 4, 2023

    Published Online: Nov. 1, 2023

    The Author Email: Yunhai Zhang (zhangyh@sibet.ac.cn)

    DOI:10.3788/CJL230943

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