Journal of Radiation Research and Radiation Processing, Volume. 41, Issue 1, 010304(2023)

Therapeutic effect of Potentilla anserina L polysaccharide on mice injured by 60Co γ ray irradiation

Daiyan WU, Yangyang FENG, Linzi ZHANG, Qianqian LIU, Hangyu LI, Jianzhenma YANG, and Haibo FENG*
Author Affiliations
  • College of Animal Husbandry and Veterinary Medicine, Southwest Minzu University, Chengdu 610041, China
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    Figures & Tables(8)
    Routine blood analysis: (a) RBC; (b) HGB; (c) HCT; (d)WBC
    Effects of PAP on the spleen index of mice
    Effects of PAP on the liver SOD in 60Co-γ radiation-induced mice
    Effects of PAP on the liver T-AOC in 60Co γ radiation-induced mice
    Effects of PAP on the liver MDA in 60 Co γ radiation-induced mice
    Lymphocyte subsets: (a) proportion of CD3+ lymphocytes; (b) proportion of CD4+ lymphocytes; (c) proportion of CD8+ lymphocytes
    Compared with 0 Gy 0.5 mL distilled water, effects of PAP on the DNA coefficient of bone marrow of mice
    • Table 1. Groups and plan

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      Table 1. Groups and plan

      组别

      Groups

      处理方式

      Methods

      灌胃剂量 /(1次∙d-1

      Gavage dose

      灌胃时间 / d

      Gavage time

      1

      不照射

      Not irradiated

      0.5 mL蒸馏水

      0.5 mL distilled water

      5
      2

      不照射

      Not irradiated

      0.5 mL蕨麻多糖(150 mg/kg B.W.) 0.5 mL PAP (150 mg/kg B.W.)5
      3

      不照射

      Not irradiated

      0.5 mL蕨麻多糖(300 mg/kg B.W.) 0.5 mL PAP (300 mg/kg B.W.)5
      4

      不照射

      Not irradiated

      0.5 mL蕨麻多糖(600 mg/kg B.W.) 0.5 mL PAP (600 mg/kg B.W.)5
      5

      5 Gy γ 射线照射,剂量率为0.8 Gy/min

      5 Gy γ ray irradiation with a dose rate of 0.8 Gy/min

      0.5 mL蒸馏水

      0.5 mL distilled water

      5
      6

      5 Gy γ 射线照射,剂量率为0.8 Gy/min

      5 Gy γ ray irradiation with a dose rate of 0.8 Gy/min

      0.5 mL蕨麻多糖(150 mg/kg B.W.) 0.5 mL PAP (150 mg/kg B.W.)5
      7

      5 Gy γ 射线照射,剂量率为0.8 Gy/min

      5 Gy γ ray irradiation with a dose rate of 0.8 Gy/min

      0.5 mL蕨麻多糖(300 mg/kg B.W.) 0.5 mLPAP (300 mg/kg B.W.)5
      8

      5 Gy γ 射线照射,剂量率为0.8 Gy/min

      5 Gy γ ray irradiation with a dose rate of 0.8 Gy/min

      0.5 mL蕨麻多糖(600 mg/kg B.W.) 0.5 mL PAP (600 mg/kg B.W.)5
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    Daiyan WU, Yangyang FENG, Linzi ZHANG, Qianqian LIU, Hangyu LI, Jianzhenma YANG, Haibo FENG. Therapeutic effect of Potentilla anserina L polysaccharide on mice injured by 60Co γ ray irradiation[J]. Journal of Radiation Research and Radiation Processing, 2023, 41(1): 010304

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    Paper Information

    Category: Research Articles

    Received: Aug. 16, 2022

    Accepted: Oct. 27, 2022

    Published Online: Mar. 6, 2023

    The Author Email:

    DOI:10.11889/j.1000-3436.2022-0080

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