Adaptive optical microscopy via virtual-imaging-assisted wavefront sensing for high-resolution tissue imaging

Zhou Zhou; Jiangfeng Huang; Xiang Li; Xiujuan Gao; Zhongyun Chen; Zhenfei Jiao; Zhihong Zhang; Qingming Luo; Ling Fu

doi:10.1186/s43074-022-00060-6

PhotoniX, Volume. 3, Issue 1, 13(2022)

Adaptive optical microscopy via virtual-imaging-assisted wavefront sensing for high-resolution tissue imaging

Zhou Zhou^1,2, Jiangfeng Huang^1,2, Xiang Li^1,2, Xiujuan Gao^1,2, Zhongyun Chen^1,2, Zhenfei Jiao^1,2, Zhihong Zhang^1,2, Qingming Luo^1,2,3, and Ling Fu^1,2、*

Author Affiliations

¹Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics-Huazhong University of Science and Technology, Wuhan 430074, China

²MoE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan 430074, China

³School of Biomedical Engineering, Hainan University, Haikou 570228, China

show less

References(32)

[1] [1] Kubby JA. Adaptive Optics for Biological Imaging. Boca Raton: CRC Press; 2013.

[2] [2] Ahn C, Hwang B, Nam K, Jin H, Woo T, Park J-H. Overcoming the penetration depth limit in optical microscopy: adaptive optics and wavefront shaping. J Innovative Optical Health Sci. 2019;12(04):1930002.10.1142/S1793545819300027

[3] [3] Booth MJ. Adaptive optical microscopy: the ongoing quest for a perfect image. Light Sci Appl. 2014;3(4):e165.10.1038/lsa.2014.46

[4] [4] Ji N. Adaptive optical fluorescence microscopy. Nat Methods. 2017;14(4):374–80.10.1038/nmeth.4218

[5] [5] Wang K, Sun W, Richie CT, Harvey BK, Betzig E, Ji N. Direct wavefront sensing for high-resolution in vivo imaging in scattering tissue. Nat Commun. 2015;6(1):7276.10.1038/ncomms8276

[6] [6] Tao X, Fernandez B, Azucena O, Fu M, Garcia D, Zuo Y, et al. Adaptive optics confocal microscopy using direct wavefront sensing. Opt Lett. 2011;36(7):1062–4.10.1364/OL.36.001062

[7] [7] Azucena O, Crest J, Kotadia S, Sullivan W, Tao X, Reinig M, et al. Adaptive optics wide-field microscopy using direct wavefront sensing. Opt Lett. 2011;36(6):825–7.10.1364/OL.36.000825

[8] [8] Débarre D, Botcherby EJ, Watanabe T, Srinivas S, Booth MJ, Wilson T. Image-based adaptive optics for two-photon microscopy. Opt Lett. 2009;34(16):2495–7.10.1364/OL.34.002495

[9] [9] Débarre D, Booth MJ, Wilson T. Image based adaptive optics through optimisation of low spatial frequencies. Opt Express. 2007;15(13):8176–90.10.1364/OE.15.008176

[10] [10] Booth MJ. Wavefront sensorless adaptive optics for large aberrations. Opt Lett. 2007;32(1):5–7.10.1364/OL.32.000005

[11] [11] Ji N, Milkie DE, Betzig E. Adaptive optics via pupil segmentation for high-resolution imaging in biological tissues. Nat Methods. 2010;7(2):141–7.10.1038/nmeth.1411

[12] [12] Chen W, Natan RG, Yang Y, Chou S-W, Zhang Q, Isacoff EY, et al. In vivo volumetric imaging of calcium and glutamate activity at synapses with high spatiotemporal resolution. Nat Commun. 2021;12(1):6630.10.1038/s41467-021-26965-7

[13] [13] Ji N, Sato TR, Betzig E. Characterization and adaptive optical correction of aberrations during in vivo imaging in the mouse cortex. Proc Natl Acad Sci. 2012;109(1):22.10.1073/pnas.1109202108

[14] [14] Milkie DE, Betzig E, Ji N. Pupil-segmentation-based adaptive optical microscopy with full-pupil illumination. Opt Lett. 2011;36(21):4206–8.10.1364/OL.36.004206

[15] [15] Wang C, Liu R, Milkie DE, Sun W, Tan Z, Kerlin A, et al. Multiplexed aberration measurement for deep tissue imaging in vivo. Nat Methods. 2014;11(10):1037–40.10.1038/nmeth.3068

[16] [16] Maurer C, Jesacher A, Bernet S, Ritsch-Marte M. What spatial light modulators can do for optical microscopy. Laser Photonics Rev. 2011;5(1):81–101.10.1002/lpor.200900047

[17] [17] Gould TJ, Burke D, Bewersdorf J, Booth MJ. Adaptive optics enables 3D STED microscopy in aberrating specimens. Opt Express. 2012;20(19):20998–1009.10.1364/OE.20.020998

[18] [18] Patton BR, Burke D, Owald D, Gould TJ, Bewersdorf J, Booth MJ. Three-dimensional STED microscopy of aberrating tissue using dual adaptive optics. Opt Express. 2016;24(8):8862–76.10.1364/OE.24.008862

[19] [19] Wang P, Slipchenko MN, Mitchell J, Yang C, Potma EO, Xu X, et al. Far-field imaging of non-fluorescent species with subdiffraction resolution. Nat Photonics. 2013;7(6):449–53.10.1038/nphoton.2013.97

[20] [20] Zhao G, Rong Z, Kuang C, Zheng C, Liu X. 3D fluorescence emission difference microscopy based on spatial light modulator. J Innov Optical Health Sci. 2016;9(03):1641003.10.1142/S1793545816410030

[21] [21] Tian N, Fu L, Gu M. Resolution and contrast enhancement of subtractive second harmonic generation microscopy with a circularly polarized vortex beam. Sci Rep. 2015;5(1):13580.10.1038/srep13580

[22] [22] Southwell WH. Wave-front estimation from wave-front slope measurements. J Opt Soc Am. 1980;70(8):998–1006.10.1364/JOSA.70.000998

[23] [23] Panagopoulou SI, Neal DP. Zonal matrix iterative method for wavefront reconstruction from gradient measurements. J Refract Surg. 2005;21(5):S563–S9.10.3928/1081-597X-20050901-28

[24] [24] Kuang C, Li S, Liu W, Hao X, Gu Z, Wang Y, et al. Breaking the diffraction barrier using fluorescence emission difference microscopy. Sci Rep. 2013;3(1):1441.10.1038/srep01441

[25] [25] Dehez H, Piché M, De Koninck Y. Resolution and contrast enhancement in laser scanning microscopy using dark beam imaging. Opt Express. 2013;21(13):15912–25.10.1364/OE.21.015912

[26] [26] Rodríguez C, Chen A, Rivera JA, Mohr MA, Liang Y, Natan RG, et al. An adaptive optics module for deep tissue multiphoton imaging in vivo. Nat Methods. 2021;18(10):1259–64.10.1038/s41592-021-01279-0

[27] [27] Wang C, Ji N. Pupil-segmentation-based adaptive optical correction of a high-numerical-aperture gradient refractive index lens for two-photon fluorescence endoscopy. Opt Lett. 2012;37(11):2001–3.10.1364/OL.37.002001

[28] [28] Leutenegger M, Rao R, Leitgeb RA, Lasser T. Fast focus field calculations. Opt Express. 2006;14(23):11277–91.10.1364/OE.14.011277

[29] [29] Zipfel WR, Williams RM, Webb WW. Nonlinear magic: multiphoton microscopy in the biosciences. Nat Biotechnol. 2003;21(11):1369–77.10.1038/nbt899

[30] [30] Zhou W, Bovik AC, Sheikh HR, Simoncelli EP. Image quality assessment: from error visibility to structural similarity. IEEE Trans Image Process. 2004;13(4):600–12.10.1109/TIP.2003.819861

[31] [31] Qi S, Li H, Lu L, Qi Z, Liu L, Chen L, et al. Long-term intravital imaging of the multicolor-coded tumor microenvironment during combination immunotherapy. eLife. 2016;5:e14756.10.7554/eLife.14756

[32] [32] Shen Z, Lu Z, Chhatbar PY, O'Herron P, Kara P. An artery-specific fluorescent dye for studying neurovascular coupling. Nat Methods. 2012;9(3):273–6.10.1038/nmeth.1857

Tools

Get Citation

Copy Citation Text

Zhou Zhou, Jiangfeng Huang, Xiang Li, Xiujuan Gao, Zhongyun Chen, Zhenfei Jiao, Zhihong Zhang, Qingming Luo, Ling Fu. Adaptive optical microscopy via virtual-imaging-assisted wavefront sensing for high-resolution tissue imaging[J]. PhotoniX, 2022, 3(1): 13

Download Citation

EndNote(RIS)BibTex Plain Text

Set citation alerts for article

Save article for my favorites

Paper Information

Category: Research Articles

Received: Mar. 23, 2022

Accepted: May. 13, 2022

Published Online: Jul. 10, 2023

The Author Email: Ling Fu (lfu@hust.edu.cn)

DOI:10.1186/s43074-022-00060-6

Topics

laser devices and laser physics

Lasers and Laser Optics

Laser physics

laser manufacturing

Instrumentation, Measurement and Metrology