Fig. 1. (a) Photoacoustic (PA) imaging system experimental setups; (b) System lateral resolution; (c) System axial resolution

Fig. 2. (a) Optical photographs of WT and AD rat brain tissue and coronal sections (blue dashed lines indicating the location of the coronal section); (b) Coronal PA imaging of WT and AD mice brain; (c) Statistical graph of amplitude distribution of PA signal in cortex of WT mouse; (d) Statistical graph of amplitude distribution of PA signal in cortex of AD mouse

Fig. 3. (a) Optical photograph of brain tissue of WT and AD mice; (b) PA imaging of WT and AD mice brain tissue; (c) Coronal PA imaging of WT and AD mice brain tissue along the blue dotted line in (a); (d) Transverse PA imaging at a depth of 0.6 mm in WT and AD mouse brain tissue

Fig. 4. (a) PA imaging of WT mouse cerebral blood vessels; (b) PA depth coding imaging of WT mouse cerebral vessels; (c) PA imaging of AD mouse cerebral vessels; (d) PA depth coding imaging of AD mouse cerebral vessel