Journal of Infrared and Millimeter Waves, Volume. 39, Issue 5, 553(2020)

Study of in-vivo breast cancer in a subcutaneous xenograft mouse model using terahertz imaging

Li-Min WU1,2, Bin LIAO3, De-Gang XU1,2, Yu-Ye WANG1,2,3、*, Mei-Lan GE1,2, Chao-Nan ZHANG4, Jia-Hua LI4, Zhong-Cheng SUN1,2, Tu-Nan CHEN3, Hua FENG3, and Jian-Quan YAO1,2
Author Affiliations
  • 1Institute of Laser and Optoelectronics, School of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin300072, China
  • 2Key Laboratory of Optoelectronics Information Technology (Ministry of Education), Tianjin University, Tianjin300072, China
  • 3Institute of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing;400038, China
  • 4School of Life Sciences, Tianjin Engineering Center of Micro-Nano Biomaterials, Tianjin University, Tianjin300072, China
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    Figures & Tables(9)
    Schematic diagram of continuous THz wave reflection imaging system
    Measurement of the focal spot size by the knife-edge method
    The subcutaneous breast cancer of mouse model
    The sample is (a) not and (b) in close contact with the reflection window
    Breast cancer tissue of mouse (a) the visual images of sample in contact with reflection window and (b) reflection images of THz wave. (a) The white dotted area is the tumor in contact with reflection window and (b) The black dotted area is the normal tissue in contact with reflection window.
    (a), (b) and (c) show the normalized relative reflectivity of the horizontal purple dotted lines of Fig.3 (b) NO.1, NO.2 and NO.3, respectively.
    The freshly excised breast cancer tissue of mice
    Staining images of freshly excised breast cancer tissue (NO.1) at different depths from skin surface
    • Table 1. 距离皮肤表面不同深度组织病理染色图中的肿瘤面积

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      Table 1. 距离皮肤表面不同深度组织病理染色图中的肿瘤面积

      d=2602.25d=4608.25d=86053.25
      d=3202.75d=5208.80d=92070.50
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    Li-Min WU, Bin LIAO, De-Gang XU, Yu-Ye WANG, Mei-Lan GE, Chao-Nan ZHANG, Jia-Hua LI, Zhong-Cheng SUN, Tu-Nan CHEN, Hua FENG, Jian-Quan YAO. Study of in-vivo breast cancer in a subcutaneous xenograft mouse model using terahertz imaging[J]. Journal of Infrared and Millimeter Waves, 2020, 39(5): 553

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    Paper Information

    Category: Millimeter Wave and Terahertz Technology

    Received: Sep. 26, 2019

    Accepted: --

    Published Online: Dec. 29, 2020

    The Author Email: Yu-Ye WANG (yuyewang@tju.edu.cn)

    DOI:10.11972/j.issn.1001-9014.2020.05.004

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