Application of Soft-Glass Optical Fibers in Biosensing

Xue Zhou; Xin Yan; Xuenan Zhang; Fang Wang; Shuguang Li; Lei Lang; Tonglei Cheng

doi:10.3788/LOP202158.1516019

Laser & Optoelectronics Progress, Volume. 58, Issue 15, 1516019(2021)

Application of Soft-Glass Optical Fibers in Biosensing

Xue Zhou¹, Xin Yan¹, Xuenan Zhang¹, Fang Wang¹, Shuguang Li¹, Lei Lang², and Tonglei Cheng^1、*

¹State Key Laboratory of Synthetical Automation for Process Industries, College of Information Science and Engineering, Northeastern University, Shenyang , Liaoning 110819, China

²SIASUN Robot & Automation Co., Ltd., Shenyang , Liaoning 110819, China

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Figures & Tables(15)

Fig. 1. Transmission spectra of several soft-glass materials^[2]

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Fig. 2. Transmission spectra of different soft glass materials. (a) Different element component; (b) different element content

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Fig. 3. Manufacturing process of chalcogenide glasses

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Fig. 4. Physical drawings of common soft glass materials

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Fig. 5. Schematic diagram of stacking method

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Fig. 6. Schematic diagram of foundry method

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Fig. 7. Diagram of sensor structure

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Fig. 8. Experimental system diagram of brain temperature detection in vivo

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Fig. 9. Soft glass fiber sensing probe based on evanescent field principle. (a) Winding sensing probe; (b) curved sensing probe

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Fig. 10. CO₂ concentration detection device

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Fig. 11. CLSM image of MG63 cells cultured on the surface of phosphate glass fibres^[68]

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Table 1. Basic properties of soft-glass fibers^{[7, 20-23]}

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Table 1. Basic properties of soft-glass fibers^{[7, 20-23]}

Property	Chalcogenide（Ge₃₀As₁₀Se₃₀Te₃₀）	Tellurite（TeO₂）	ZBLAN（ZrF₄-BaF₂-LaF₃-AlF₃-NaF）	Phosphate（20 K₂O-10MgO-10Al₂O₃-60P₂O₅）	Silica
Approximate transmission range /μm	2‒12	0.4‒20	0.22-8		0.16‒4
Maximum phonon energy /cm^-1	450		600		1100
Transition temperature /℃	265	280‒430	260	470@PAL 01	1175
Thermal conductivity /（W·m^-1∙K^-1）	~0.2		0.628		1.38
Expansion coefficient /（10^-6 K^-1）	14.4	18.6	17.2	10	0.55
Density （g·cm^-3）	4.88	5.001@TeO₂-NaCl	4.3	2.87	2.20
Knoop hardness （kg·mm^-2）	205		225		600
Fracture toughness /（MPa·m^1/2）	~0.2		0.32		0.72
Poisson’s ratio	~0.26		0.17		0.17
Young’s modulus /GPa	21.9		58.3		70
Refractive index	2.9@2 μm	2.24@1900 nm	1.499@589 nm	1.6@1.5 μm	1.458@589 nm
Nonlinear index/（cm²·W^-1）	9.2×10^-14	1.7×10^-14	1.2×10^-14		4.5×10^-14
Thermo-optic coefficient /（10^-6 K^-1）	10	-16.4	-14.75		11.9

Table 2. Simulation results of multimode fiber grating (MM-FBG) based on Ge-Sb-Se material^[37]

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Table 2. Simulation results of multimode fiber grating (MM-FBG) based on Ge-Sb-Se material^[37]

Core material	Cladding material	Temperature sensitivity /（nm · °C^-1）
Ge₂₈Sb₁₂Se₆₀（2.6601）	Ge₂₅Sb₁₅Se₆₀（2.6500）	0.075670
Ge₂₈Sb₁₂Se₆₀（2.6601）	Ge₂₀Sb₁₅Se₆₅（2.4621）	0.076660
Ge₂₈Sb₁₂Se₆₀（2.6601）	Ge₁₅Sb₂₅Se₆₀（2.4500）	0.076660
Ge₂₅Sb₁₅Se₆₀（2.6500）	Ge₂₀Sb₁₅Se₆₅（2.4621）	0.065333
Ge₂₅Sb₁₅Se₆₀（2.6500）	Ge₁₅Sb₂₅Se₆₀（2.4500）	0.065333
Silica（1.4628）	Silica（1.4681）	0.011000

Table 3. Simulation results of Ge-Sb-Se MM-FBG for different operation wavelengths^[37]

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Table 3. Simulation results of Ge-Sb-Se MM-FBG for different operation wavelengths^[37]

Core material	Cladding material	Bragg wavelength /nm	Temperature sensitivity /（nm · °C^-1）
Ge₂₈Sb₁₂Se₆₀	Ge₂₅Sb₁₅Se₆₀	1550	0.075670
		2000	0.098000
		3390	0.166000
Ge₂₅Sb₁₅Se₆₀	Ge₂₀Sb₁₅Se₆₅	1550	0.065333
		2000	0.084667
		3390	0.145000

Table 4. Spectroscopic and sensing parameters for various Er³⁺ hosting matrix^[14]

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Table 4. Spectroscopic and sensing parameters for various Er³⁺ hosting matrix^[14]

Rare earth ion hosting matrix	Excitation wavelength /nm	Temperature range /K	Pre-exponential factor	Energy gap /cm^-1	Maximum sensitivity /K^-1	Maximun temperature /K
Silicate glass： Er³⁺	978	296‒673	1.87	512	0.0023
Tellurite glass： Er³⁺	379	313‒713	13.6	781	0.0085	596
Germanate glass： Er³⁺	379	453‒713	18.8	827	0.0066	473
Chalcogenide glass： Er³⁺/Yb³⁺	1060	293‒498	8.85	645	0.0052	493
Tellurite-Germanate glass： Er³⁺	379	313‒713	17.30	830	0.0078	599
Fluorophosphates glass： Er³⁺	488	298‒773	18.37	873	0.0079	630
Fluorotellurite glass： Er³⁺	800	300‒500	10.25	765	0.0054	547
Flurotellurite glass： Er³⁺	476.5	83‒863	14.67	766	0.0072	547
Er³⁺	514	83‒863	14.02	759	0.0069	550

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Xue Zhou, Xin Yan, Xuenan Zhang, Fang Wang, Shuguang Li, Lei Lang, Tonglei Cheng. Application of Soft-Glass Optical Fibers in Biosensing[J]. Laser & Optoelectronics Progress, 2021, 58(15): 1516019

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Paper Information

Category: Materials

Received: Dec. 7, 2020

Accepted: Feb. 3, 2021

Published Online: Aug. 11, 2021

The Author Email: Tonglei Cheng (chengtonglei@ise.neu.edu.cn)

DOI:10.3788/LOP202158.1516019

Topics

laser devices and laser physics

Lasers and Laser Optics

Laser physics

laser manufacturing

Instrumentation, Measurement and Metrology

Table 1. Basic properties of soft-glass fibers[7, 20-23]

Table 1. Basic properties of soft-glass fibers[7, 20-23]

Table 2. Simulation results of multimode fiber grating (MM-FBG) based on Ge-Sb-Se material[37]

Table 2. Simulation results of multimode fiber grating (MM-FBG) based on Ge-Sb-Se material[37]

Table 3. Simulation results of Ge-Sb-Se MM-FBG for different operation wavelengths[37]

Table 3. Simulation results of Ge-Sb-Se MM-FBG for different operation wavelengths[37]

Table 4. Spectroscopic and sensing parameters for various Er3+ hosting matrix[14]

Table 4. Spectroscopic and sensing parameters for various Er3+ hosting matrix[14]

Table 1. Basic properties of soft-glass fibers^{[7, 20-23]}

Table 1. Basic properties of soft-glass fibers^{[7, 20-23]}

Table 2. Simulation results of multimode fiber grating (MM-FBG) based on Ge-Sb-Se material^[37]

Table 2. Simulation results of multimode fiber grating (MM-FBG) based on Ge-Sb-Se material^[37]

Table 3. Simulation results of Ge-Sb-Se MM-FBG for different operation wavelengths^[37]

Table 3. Simulation results of Ge-Sb-Se MM-FBG for different operation wavelengths^[37]

Table 4. Spectroscopic and sensing parameters for various Er³⁺ hosting matrix^[14]

Table 4. Spectroscopic and sensing parameters for various Er³⁺ hosting matrix^[14]