Herein, AlSi10Mg alloy samples were successfully fabricated along different building directions using LPBF. After static mechanical tests, the room-temperature compressive strength could reach 201.0 MPa and the yield strength was 251.3 MPa. The tensile and yield strengths at 175 ℃ could reach 195.0 and 160.0 MPa, respectively. The static mechanical tests of the samples along different building directions revealed that the horizontal samples showed with better compression properties at room temperature and better tensile properties at a high temperature than the vertical samples. The LPBF-processed AlSi10Mg vertical sample showed excellent 10⁷-cycle median fatigue strength of 151.25 MPa, while relevant research shows that the high cycle fatigue strength of AlSi12 alloys processed using LAM is 88.7 MPa. The excellent high-cycle fatigue resistance of AlSi10Mg processed using LAM was attributed to its unique fine cellular grains and fine Al-Si eutectic phases at grain boundaries. The fatigue life and threshold of fatigue crack growth of the LPBF-processed AlSi10Mg alloy were ~2.1×10⁵ cycles and 0.981 MPa·m^1/2, respectively. The findings of this study show that the excellent mechanical properties of AlSi10Mg alloys can be obtained by LPBF processing. This study can provide an academic reference for the application of LAM-processed aluminum alloys in aerospace and other fields.