Chinese Journal of Lasers, Volume. 46, Issue 1, 107001(2019)

Multi-Channel Brain Functional Imaging System Based on Lock-in Photon Counting

Ding Xuemei1, Wang Bingyuan1, Liu Dongyuan1, Zhang Yao1, Pan Tiantian1, and Gao Feng1,2
Author Affiliations
  • 1[in Chinese]
  • 2[in Chinese]
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    Figures & Tables(11)
    Overall structure block diagram of imaging system
    (a) Structure of digital lock-in demodulator; (b) phase characteristics of lock-in in square mode
    Structural diagram of lock-in photon counting hardware logic implementation
    Linearity assessments of the system
    Ability of the system to overcome ambient light
    Crosstalk ratio between channels at different frequency spaces. (a) Frequency space of 50 Hz; (b) frequency space of 200 Hz; (c) frequency space of 252 Hz
    Schematics of solid-state phantom in experiment. (a) Three-dimensional structure; (b) top view
    Scan schemes
    DOT reconstruction under 7-time excitation
    • Table 1. Peak signal to noise ratio of the system

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      Table 1. Peak signal to noise ratio of the system

      Integrationtime /msSignal to noise ratio /dB
      one LDsix LDssixteen LDs
      30044.2737.7234.38
      50047.8941.1535.52
      100050.2842.8337.87
    • Table 2. Optical parameters of liquid phantom

      View table

      Table 2. Optical parameters of liquid phantom

      OpticalparameterBackgroundContrast of target
      1.21.52.0
      μa /mm-10.01730.020760.025950.0346
      μs /mm-11.01341.01341.01341.0134
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    Ding Xuemei, Wang Bingyuan, Liu Dongyuan, Zhang Yao, Pan Tiantian, Gao Feng. Multi-Channel Brain Functional Imaging System Based on Lock-in Photon Counting[J]. Chinese Journal of Lasers, 2019, 46(1): 107001

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    Paper Information

    Category: biomedical photonics and laser medicine

    Received: Jul. 4, 2018

    Accepted: --

    Published Online: Jan. 27, 2019

    The Author Email:

    DOI:10.3788/CJL201946.0107001

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