Acta Optica Sinica, Volume. 45, Issue 4, 0430001(2025)
Real-Time Detection of Metabolic Carbon Dioxide Volume Fraction in Skin Based on Frequency-Locked Quartz-Enhanced Photoacoustic Spectroscopy
Fig. 1. Simulation of absorption spectra of CO2 and interfering gases at air volume fraction
Fig. 3. Temperature change in detection chamber under skin fit. (a) Results without temperature control; (b) results under temperature control
Fig. 4. Physical device diagram of the skin CO2 detection system based on QEPAS technology. (a) Equipment; (b) sample absorption pool; (c) detection chamber; (d) analog PID control circuit; (e) temperature controlled circuit
Fig. 5. Signals of the first harmonic frequency locking system. (a) Locking process of the first harmonic signal of the sample absorption cell; (b) second harmonic signal of QTF
Fig. 7. Test results of system response time. (a) Second harmonic signal response curve for variation of CO2 volume fraction from 0 to 2000×10-6; (b) results of exponential fitting of the volume fraction change process
Fig. 10. Schematic diagram of skin detection. (a) Detection site; (b) detection method
Fig. 11. Results of the skin CO2 detection by the system on the left arm, left palm, left cheek, and left armpit with linear fitting results for the four sites
Fig. 12. Linear fit results obtained from four identical sites of skin CO2 testing on two adjacent days for the same volunteer
Fig. 13. Schematic diagram of human detection sites and statistical results of CO2 release rates from four sites in three volunteers
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Yixin Zhang, Huakun Wu, Qiong Wu, Wen Liu, Jie Shao. Real-Time Detection of Metabolic Carbon Dioxide Volume Fraction in Skin Based on Frequency-Locked Quartz-Enhanced Photoacoustic Spectroscopy[J]. Acta Optica Sinica, 2025, 45(4): 0430001
Category: Spectroscopy
Received: Nov. 5, 2024
Accepted: Dec. 10, 2024
Published Online: Feb. 19, 2025
The Author Email: Shao Jie (shaojie@zjnu.cn)
CSTR:32393.14.AOS241710