Chinese Journal of Lasers, Volume. 50, Issue 9, 0907103(2023)

In Vivo Photoacoustic Endoscopy Imaging of Gastrointestinal Model of Septic Small-Animal

Xiaolong Chen1, Yizhi Liang1、*, Xiaoxuan Zhong1, Xue Bai1, Long Jin1, Wei Huang2, Cheng Huang3, Xiaobing Niu4, Shanshan Guo4, and Baiou Guan1
Author Affiliations
  • 1Guangdong Key Laboratory of Optical Fiber Sensing and Communication Technology, Institute of Photonics Technology, Jinan University, Guangzhou 511443, Guangdong, China
  • 2Department of Gastroenterology, First Affiliated Hospital of Jinan University, Guangzhou 510632, Guangdong, China
  • 3Guangdong Cardiovascular Institute, Guangdong Provincial People s Hospital, Guangzhou 510080, Guangdong, China
  • 4Guangzhou SINCHOO Medical Technology Co., Ltd., Guangzhou 510535, Guangdong, China
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    Figures & Tables(5)
    Photoacoustic endoscopic imaging probe and system. (a) Schematic of photoacoustic imaging system; (b) schematic of spiral scanning and imaging; (c) structural diagram of endoscopic probe; (d) cross sectional structure of endoscopic probe; (e) schematic of depth of field and imaging depth; (f) photo of endoscopic imaging system
    Imaging performance characterization of endoscopic probe. (a) Characterization method and (c) results of lateral spatial resolution; (b) characterization method and (d) results of stability
    Photoacoustic endoscopic imaging results of intestinal tract of healthy small animals. (a) Scanning diagram; (b) three dimensional distribution of blood vessels in inner wall of rectum; (c) 2D spatial distribution of normalized amplitude of photoacoustic signal; (d) 2D spatial distribution of blood oxygen saturation; (e) 2D spatial distribution of blood vessel depth
    Photoacoustic endoscopic imaging results of intestinal tract of healthy rat. (a) Normalized amplitude of photoacoustic signal; (b) blood oxygen saturation
    Imaging results of intestinal model in septic rats. (a) Normalized amplitude of photoacoustic signal; (b) blood oxygen saturation
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    Xiaolong Chen, Yizhi Liang, Xiaoxuan Zhong, Xue Bai, Long Jin, Wei Huang, Cheng Huang, Xiaobing Niu, Shanshan Guo, Baiou Guan. In Vivo Photoacoustic Endoscopy Imaging of Gastrointestinal Model of Septic Small-Animal[J]. Chinese Journal of Lasers, 2023, 50(9): 0907103

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    Paper Information

    Category: Biomedical Optical Imaging

    Received: Nov. 24, 2022

    Accepted: Jan. 12, 2023

    Published Online: Apr. 24, 2023

    The Author Email: Liang Yizhi (liangyizhi88528@gmail.com)

    DOI:10.3788/CJL221450

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