Supercontinuum generation (SC) in photonic crystal fibers (PCFs) with two zero dispersion wavelengths is investigated numerically, and the mechanism of SC generation in both normal dispersion region pumping and abnormal dispersion region pumping is analyzed. In order to investigate the effect of structure parameters, SC generation in four different PCFs is analyzed. And the influence of two zero dispersion wavelengths is investigated. In addition, a method for SC control on spectral width and energy distribution by designing structure parameters is proposed.