Journal of Radiation Research and Radiation Processing, Volume. 40, Issue 6, 060301(2022)
Study on the therapeutic mechanism and effect of metformin combined with single high-dose radiotherapy in mice with non-small cell lung cancer
[1] WU Guangbo. Progress in application of metformin in radiotherapy for malignant tumors[J]. Chinese Journal of Clinical Oncology, 48, 45-49(2021).
[2] YANG Luo, HAO Yarong. Research progress on pharmacological effects of metformin[J]. Medical Recapitulate, 25, 1816-1821(2019).
[3] WANG Gaoxiang, XU Meiqing, XIE Mingran. Research advance in anti-lung cancer mechanism of metformin[J]. Chinese Journal of Lung Cancer, 23, 282-285(2020).
[4] MU Chunqing, ZHOU Lei, ZHAO Nan et al. Effect of metformin on proliferation of lung cancer A549 cells through PI3K/AKT/GSK3β signaling pathway[J]. Journal of Jilin University (Medicine Edition), 47, 637-643(2021).
[5] Song C W, Lee Y J, Griffin R J et al. Indirect tumor cell death after high-dose hypofractionated irradiation: implications for stereotactic body radiation therapy and stereotactic radiation surgery[J]. International Journal of Radiation Oncology*Biology*Physics, 93, 166-172(2015).
[6] Matthews Q, Isabelle M, Harder S J et al. Radiation-induced glycogen accumulation detected by single cell Raman spectroscopy is associated with radioresistance that can Be reversed by metformin[J]. PLoS One, 10, e0135356(2015).
[7] Brown S L, Kolozsvary A, Isrow D M et al. A novel mechanism of high dose radiation sensitization by metformin[J]. Frontiers in Oncology, 9, 247(2019).
[8] GUO Wanyi, YUAN Bei, ZHANG Nixue et al. Effect of reactive oxygen species (ROS) on bone destruction in rheumatoid arthritis[J]. Chinese Journal of Immunology, 37, 2182-2186(2021).
[9] YANG Riyun, PAN Jingying, LI Yi et al. Protective effect of menaquinone-4 on oligodendrocytes under hypoxia[J]. Chinese Journal of Anatomy, 43, 388-392(2020).
[10] Elgendy M, Cirò M, Hosseini A et al. Combination of hypoglycemia and metformin impairs tumor metabolic plasticity and growth by modulating the PP2A-GSK3β-MCL-1 axis[J]. Cancer Cell, 35, 798-815(2019).
[11] GUO Qian, REN Qianmei, MAO Xiguang et al. Effect of metformin on proliferation and chemosensitivity of cervical cancer stem cells[J]. Chinese Journal of Gerontology, 41, 5351-5356(2021).
[12] QIAO Lu, JIA Yitao. Research progress of metformin in the treatment of colorectal cancer[J]. Journal of Digestive Oncology (Electronic Version), 13, 25-28(2021).
[13] SUN Yucheng, LIU Xiaowei, PIAN Guangzhe. Effect of metformin on radiosensitivity of rectal cancer cells[J]. Chinese Journal of Oncology Prevention and Treatment, 11, 37-42(2019).
[14] Dowling R J O, Lam S, Bassi C et al. Metformin pharmacokinetics in mouse tumors: implications for human therapy[J]. Cell Metabolism, 23, 567-568(2016).
[15] LI Meiye, XU Wenchao, QU Wei et al. The effects of metformin on survival of diabetic patients complicated with lung cancer[J]. Labeled Immunoassays and Clinical Medicine, 27, 1147-1150(2020).
Get Citation
Copy Citation Text
Huichao LI, Mingjuan ZHAO, Long TIAN. Study on the therapeutic mechanism and effect of metformin combined with single high-dose radiotherapy in mice with non-small cell lung cancer[J]. Journal of Radiation Research and Radiation Processing, 2022, 40(6): 060301
Category: Research Articles
Received: Apr. 11, 2022
Accepted: May. 1, 2022
Published Online: Jan. 4, 2023
The Author Email: Long TIAN (1277473912@qq.com)