Chinese Journal of Lasers, Volume. 52, Issue 8, 0802408(2025)

Femtosecond Laser Additive-Removal Bimodal Fabrication of Protein-Hydrogel-Based Three-Dimensional Micro/Nano-Structures

Yun Liu1... Hanxuan Huang1, Zifeng Xiao1, Yongjun Yan2, Xunren Zheng2 and Yunlu Sun1,* |Show fewer author(s)
Author Affiliations
  • 1School of Information Science and Technology, Fudan University, Shanghai 200082, China
  • 2Department of Mechanical and Automation Engineering, the Chinese University of Hong Kong, Hong Kong 999077, China
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    Figures & Tables(5)
    Schematic showing femtosecond laser two-photon direct-write micro/nano-fabrication system
    Principle of hydrogel crosslinking. (a) Preparation principle of hydrogel curing precursor solution; (b) photocuring of hydrogels under the action of femtosecond laser
    Effects of different parameters on the structure of hydrogel photocrosslinked structure and hydrogel loading sample cassettes. (a) SEM images of rectangular blocks of photocrosslinked hydrogel under the conditions of same power and different point dwell time and line spacings; (b) optical microscopy image of rectangular blocks of photocrosslinked hydrogel with 100 μs point dwell time; (c) optical microscopy view of laser additive rectangular blocks with different line spacings; (d) optical microscopy view of additively manufactured hemispheroids with different radii
    Hydrogel-loaded sample cassette structure and the pictures of UV single-photon cured hydrogel. (a) Schematic of sample cassette structure; (b) the pictures showing UV single-photon cured hydrogel
    Effect of different parameters on hydrogel photoablation structures. (a) Optical microscopy image of hydrogel photoablation structures with different laser powers; (b) optical microscopy image and fluorescence effect images of hydrogel photoablation structures with different scanning times; (c) optical microscopy image of long-distance hydrogel photoablation microchannels with different diameters; (d) optical microscopy image of hydrogel photoablation heterostructure
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    Yun Liu, Hanxuan Huang, Zifeng Xiao, Yongjun Yan, Xunren Zheng, Yunlu Sun. Femtosecond Laser Additive-Removal Bimodal Fabrication of Protein-Hydrogel-Based Three-Dimensional Micro/Nano-Structures[J]. Chinese Journal of Lasers, 2025, 52(8): 0802408

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    Paper Information

    Category: Laser Micro-Nano Manufacturing

    Received: Nov. 14, 2024

    Accepted: Dec. 13, 2024

    Published Online: Mar. 20, 2025

    The Author Email: Yunlu Sun (ylsun@fudan.edu.cn)

    DOI:10.3788/CJL241345

    CSTR:32183.14.CJL241345

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