Chinese Journal of Lasers, Volume. 52, Issue 8, 0802408(2025)
Femtosecond Laser Additive-Removal Bimodal Fabrication of Protein-Hydrogel-Based Three-Dimensional Micro/Nano-Structures
Fig. 1. Schematic showing femtosecond laser two-photon direct-write micro/nano-fabrication system
Fig. 2. Principle of hydrogel crosslinking. (a) Preparation principle of hydrogel curing precursor solution; (b) photocuring of hydrogels under the action of femtosecond laser
Fig. 3. Effects of different parameters on the structure of hydrogel photocrosslinked structure and hydrogel loading sample cassettes. (a) SEM images of rectangular blocks of photocrosslinked hydrogel under the conditions of same power and different point dwell time and line spacings; (b) optical microscopy image of rectangular blocks of photocrosslinked hydrogel with 100 μs point dwell time; (c) optical microscopy view of laser additive rectangular blocks with different line spacings; (d) optical microscopy view of additively manufactured hemispheroids with different radii
Fig. 4. Hydrogel-loaded sample cassette structure and the pictures of UV single-photon cured hydrogel. (a) Schematic of sample cassette structure; (b) the pictures showing UV single-photon cured hydrogel
Fig. 5. Effect of different parameters on hydrogel photoablation structures. (a) Optical microscopy image of hydrogel photoablation structures with different laser powers; (b) optical microscopy image and fluorescence effect images of hydrogel photoablation structures with different scanning times; (c) optical microscopy image of long-distance hydrogel photoablation microchannels with different diameters; (d) optical microscopy image of hydrogel photoablation heterostructure
Get Citation
Copy Citation Text
Yun Liu, Hanxuan Huang, Zifeng Xiao, Yongjun Yan, Xunren Zheng, Yunlu Sun. Femtosecond Laser Additive-Removal Bimodal Fabrication of Protein-Hydrogel-Based Three-Dimensional Micro/Nano-Structures[J]. Chinese Journal of Lasers, 2025, 52(8): 0802408
Category: Laser Micro-Nano Manufacturing
Received: Nov. 14, 2024
Accepted: Dec. 13, 2024
Published Online: Mar. 20, 2025
The Author Email: Yunlu Sun (ylsun@fudan.edu.cn)
CSTR:32183.14.CJL241345