Laser & Optoelectronics Progress, Volume. 62, Issue 18, 1817001(2025)
NIR-II Fluorescence Guided Surgery Technology and Clinical Application (Invited)
Figures & Tables(3)
Fig. 1. Schematic diagram of NIR-II fluorescence surgical navigation, the excitation light irradiates the surgical area, and the probe taken up by the tumor generates emission light to guide the surgical resection of the tumor
Table 1. Part of NIR-II imaging system
View tableTable 1. Part of NIR-II imaging system
System type System technology Experimental verification Ref. Open surgerysystem InGaAs array prototype Real-time fluorescence imaging in mice ［ 30 ］Lens-enhanced InGaAs array High-resolution （30 μm， 200 ms） mouse hindlimb vasculature ［ 31 ］Time-dimension optical chopper Multi-tumor-marker quantitative imaging ［ 32 ］Visible/NIR-I/II multispectral system First human application （liver cancer surgery） ［ 4 ］Tri-band （I/IIa/IIb） time-division Multifunctional imaging （fat， vessels， lymph） ［ 33 ］Endoscopic surgery system NIR-II endoscope framework Rat colorectal cancer model verification ［ 34 ］Microscopic system NIR-II confocal system Real-time 3D imaging （900 μm depth） ［ 36 ］TCSPC+femtosecond laser First NIR-II lifetime imaging of brain vasculature ［ 37 ］SNSPD confocal scanner Skull-penetrating imaging （2.5 mm depth， 7.5 mm×7.5 mm FOV） ［ 38 ］SNSPD+PEG-QDs 5.5 μm capillary imaging at 1.7 mm depth ［ 39 ］
Tools
Get Citation
Copy Citation Text
Ziyu Pei, Zeyu Lei, Xinchen Han, Jinze Zhao, Yifan Zhou, Lidan Fu, Jie Tian, Zhenhua Hu. NIR-II Fluorescence Guided Surgery Technology and Clinical Application (Invited)[J]. Laser & Optoelectronics Progress, 2025, 62(18): 1817001
Paper Information
Category: Medical Optics and Biotechnology
Received: Jul. 24, 2025
Accepted: Aug. 7, 2025
Published Online: Sep. 12, 2025
The Author Email: Jie Tian (tian@ieee.org), Zhenhua Hu (zhenhua.hu@ia.ac.cn)
CSTR:32186.14.LOP251758
© Copyright 2018-2021 | Chinese Laser Press.
All Rights Reserved 沪ICP备15018463号-20