Researching | Robust and rapidly tunable light source for SRS/CARS microscopy with low-intensity noise

Advanced Photonics, Volume. 1, Issue 5, 055001(2019)

Robust and rapidly tunable light source for SRS/CARS microscopy with low-intensity noise On the Cover

Heiko Linnenbank^1,2、*, Tobias Steinle^1,2, Florian Mörz^1,2, Moritz Flöss², Han Cui³, Andrew Glidle³, and Harald Giessen^1,2

Author Affiliations

¹SI Stuttgart Instruments GmbH, Öhringen, Germany

²University of Stuttgart, 4th Physics Institute and Research Center SCoPE, Stuttgart, Germany

³University of Glasgow, College of Science and Engineering, Division of Biomedical Engineering, Glasgow, United Kingdom

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References(25)

[1] W. Min et al. Coherent nonlinear optical imaging: beyond fluorescence microscopy. Annu. Rev. Phys. Chem., 62, 507-530(2011).

[2] A. Zumbusch, W. Langbein, P. Borri. Nonlinear vibrational microscopy applied to lipid biology. Progr. Lipid Res., 52, 615-632(2013).

[3] Y. Yu, P. V. Ramachandran, M. C. Wang. Shedding new light on lipid functions with CARS and SRS microscopy. Biochim. Biophys. Acta, 1841, 1120-1129(2014).

[4] F.-K. Lu et al. Label-free DNA imaging in vivo with stimulated Raman scattering microscopy. Proc. Natl. Acad. Sci. U. S. A., 112, 11624-11629(2015).

[5] M. Cicerone. Molecular imaging with CARS micro-spectroscopy. Curr. Opin. Chem. Biol., 33, 179-185(2016).

[6] C. H. Camp, M. T. Cicerone. Chemically sensitive bioimaging with coherent Raman scattering. Nat. Photonics, 9, 295-305(2015).

[7] F. Masia et al. Quantitative chemical imaging and unsupervised analysis using hyperspectral coherent anti-Stokes Raman scattering microscopy. Anal. Chem., 85, 10820-10828(2013).

[8] C. W. Freudiger et al. Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy. Science, 322, 1857-1861(2008).

[9] P. Nandakumar, A. Kovalev, A. Volkmer. Vibrational imaging based on stimulated Raman scattering microscopy. New J. Phys., 11, 033026(2009).

[10] A. Dogariu et al. Concentration dependence in coherent Raman scattering. J. Mod. Opt., 55, 3255-3261(2008).

[11] Y. Ozeki et al. Analysis and experimental assessment of the sensitivity of stimulated Raman scattering microscopy. Opt. Express, 17, 3651-3658(2009).

[12] J. Réhault et al. Broadband stimulated Raman scattering with Fourier-transform detection. Opt. Express, 23, 25235-25246(2015).

[13] W. Langbein, I. Rocha-Mendoza, P. Borri. Coherent anti-Stokes Raman micro-spectroscopy using spectral focusing: theory and experiment. J. Raman Spectrosc., 40, 800-808(2009).

[14] I. Rocha-Mendoza et al. Differential coherent anti-Stokes Raman scattering microscopy with linearly chirped femtosecond laser pulses. Opt. Lett., 34, 2258-2260(2009).

[15] F. Saltarelli et al. Broadband stimulated Raman scattering spectroscopy by a photonic time stretcher. Opt. Express, 24, 21264-21275(2016).

[16] K. Tokunaga et al. Generation of synchronized picosecond pulses by a 1.06-μm gain-switched laser diode for stimulated Raman scattering microscopy. Opt. Express, 24, 9617-9628(2016). https://doi.org/10.1364/OE.24.009617

[17] S. Karpf et al. A time-encoded technique for fibre-based hyperspectral broadband stimulated Raman microscopy. Nat. Commun., 6, 6784(2015).

[18] C. W. Freudiger et al. Stimulated Raman scattering microscopy with a robust fibre laser source. Nat. Photonics, 8, 153-159(2014).

[19] C. Riek et al. Stimulated Raman scattering microscopy by Nyquist modulation of a two-branch ultrafast fiber source. Opt. Lett., 41, 3731-3734(2016).

[20] D. A. Orringer et al. Rapid intraoperative histology of unprocessed surgical specimens via fibre-laser-based stimulated Raman scattering microscopy. Nat. Biomed. Eng., 1, 0027(2017).

[21] T. Südmeyer et al. Novel ultrafast parametric systems: high repetition rate single-pass OPG and fibre-feedback OPO. J. Phys. D, 34, 2433-2439(2001).

[22] F. Mörz et al. Multi-Watt femtosecond optical parametric master oscillator power amplifier at 43 MHz. Opt. Express, 23, 23960-23967(2015).

[23] M. Marangoni et al. Narrow-bandwidth picosecond pulses by spectral compression of femtosecond pulses in a second-order nonlinear crystal. Opt. Express, 15, 8884-8891(2007).

[24] Q. Hu, H. Zhao, S. Ouyang. Understanding water structure from Raman spectra of isotopic substitution H2O/D2. Phys. Chem. Chem. Phys., 19, 21540-21547(2017). https://doi.org/10.1039/C7CP02065A

[25] T. W. Kee, M. T. Cicerone. Simple approach to one-laser, broadband coherent anti-Stokes Raman scattering microscopy. Opt. Lett., 29, 2701-2703(2004).

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Heiko Linnenbank, Tobias Steinle, Florian Mörz, Moritz Flöss, Han Cui, Andrew Glidle, Harald Giessen, "Robust and rapidly tunable light source for SRS/CARS microscopy with low-intensity noise," Adv. Photon. 1, 055001 (2019)

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Paper Information

Category: Letters

Received: Jul. 4, 2019

Accepted: Aug. 28, 2019

Published Online: Sep. 25, 2019

The Author Email: Linnenbank Heiko (h.linnenbank@pi4.uni-stuttgart.de)

DOI:10.1117/1.AP.1.5.055001

Topics

laser devices and laser physics

Lasers and Laser Optics

laser manufacturing

Instrumentation, Measurement and Metrology