Construction and Functional Validation of GTKO/hCD55 Gene-Edited Xenotransplant Donor Pigs

WANG Jiaoxiang; ZHANG Lu; CHEN Shuhan; JIAO Deling; ZHAO Heng; WEI Taiyun; GUO Jianxiong; XU Kaixiang; WEI Hongjiang

doi:10.12300/j.issn.1674-5817.2025.024

Laboratory Animal and Comparative Medicine, Volume. 45, Issue 4, 379(2025)

Construction and Functional Validation of GTKO/hCD55 Gene-Edited Xenotransplant Donor Pigs

WANG Jiaoxiang^1,2,3, ZHANG Lu^1,2,4, CHEN Shuhan^1,2,4, JIAO Deling^1,2,4, ZHAO Heng^1,2,4, WEI Taiyun^1,2,4, GUO Jianxiong^1,2,4, XU Kaixiang^1,2,4, and WEI Hongjiang^1,2,3,4、*

Author Affiliations

¹Yunnan Province Key Laboratory for Porcine Gene Editing and Xenotransplantation, Kunming 650201, China

²Yunnan Province Xenotransplantation Research Engineering Center, Kunming 650201, China

³Faculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China

⁴College of Veterinary Medicine, Yunnan Agricultural University, Kunming 650201, China

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WANG Jiaoxiang, ZHANG Lu, CHEN Shuhan, JIAO Deling, ZHAO Heng, WEI Taiyun, GUO Jianxiong, XU Kaixiang, WEI Hongjiang. Construction and Functional Validation of GTKO/hCD55 Gene-Edited Xenotransplant Donor Pigs[J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 379

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Paper Information

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Received: Feb. 20, 2025

Accepted: Sep. 10, 2025

Published Online: Sep. 10, 2025

The Author Email: WEI Hongjiang (hongjiangwei@126.com)

DOI:10.12300/j.issn.1674-5817.2025.024

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