Acta Laser Biology Sinica, Volume. 30, Issue 3, 284(2021)

Effect of MC4R Expression Mediates the Anti-obesity Activity of Pu-erh Tea Extracts in High-fat Diet-induced Obesity in Rats

YI Juan, YIN Longwu, WANG Wei, and PENG Fenglan*
Author Affiliations
  • [in Chinese]
  • show less
    References(9)

    [1] [1] BHASKARAN K, DOUGLAS I, FORBES H, et al. Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5.24 million UK adults [J]. Lancet, 2014, 384(9945): 755-765.

    [3] [3] CAO Z H, YANG H, HE Z L, et al. Effects of aqueous extracts of raw Pu’erh tea and ripened Pu’erh tea on proliferation and differentiation of 3T3-L1 preadipocytes[J]. Phytotherapy Research, 2013, 27(8): 1193-1199.

    [10] [10] BHAT S P, SHARMA A. Current drug targets in obesity pharmacotherapy–a review [J].?Current Drug Targets, 2017, 18(8): 983-993.

    [14] [14] OOSTEROM J, GARNER K M, DEN DEKKER W K, et al. Common requirements for melanocortin-4 receptor selectivity of structurally unrelated melanocortin agonist and endogenous antagonist, agouti protein[J]. Journal of Biological Chemistry, 2001, 276(2): 931-936.

    [15] [15] JPL G, PALMER D, MELDAL M. MC4R agonists: structural overview on antiobesity therapeutics [J]. Trends in Pharmacological Sciences, 2018, 39(4): 402-423.

    [16] [16] LOTTA L A, MOKROSI?SKI J, OLIVEIRA EMD, et al. Human gain-of-function MC4R variants show signaling bias and protect against obesity [J]. Cell, 2019, 177(3): 597-607.

    [17] [17] KIM J D, LEYVA S, DIANO S. Hormonal regulation of the hypothalamic melanocortin system [J]. Frontiers in Physiology, 2014, 5: 480.

    [18] [18] EZZAT S M, EL BISHBISHY M H, ABOREHAB N M, et al. Upregulation of MC4R and PPAR-α expression mediates the anti-obesity activity of Moringa oleifera Lam. in high-fat diet-induced obesity in rats [J]. Journal of Ethnopharmacology, 2020, 251: 112541.

    [19] [19] HUANG F, WANG S, ZHAO A, et al. Pu-erh tea regulates fatty acid metabolism in mice under high-fat diet [J]. Frontiers in Pharmacology, 2019, 10: 63.

    Tools

    Get Citation

    Copy Citation Text

    YI Juan, YIN Longwu, WANG Wei, PENG Fenglan. Effect of MC4R Expression Mediates the Anti-obesity Activity of Pu-erh Tea Extracts in High-fat Diet-induced Obesity in Rats[J]. Acta Laser Biology Sinica, 2021, 30(3): 284

    Download Citation

    EndNote(RIS)BibTexPlain Text
    Save article for my favorites
    Paper Information

    Category:

    Received: Mar. 10, 2021

    Accepted: --

    Published Online: Sep. 1, 2021

    The Author Email: Fenglan PENG (26901894@qq.com)

    DOI:10.3969/j.issn.1007-7146.2021.03.011

    Topics