Journal of Inorganic Materials, Volume. 36, Issue 12, 1305(2021)

Potassium Ferrate-loaded Porphyrin-based (VI) Metal-organic Frameworks for Combined Photodymanic and Chemodynamic Tumor Therapy

Yuwei WANG*, Jiajie CHEN, Zhengfang TIAN, Min ZHU, and Yufang ZHU
Figures & Tables(11)
TEM images of (a) PCN-224, (b) Fe(VI)@PCN-224 and (c) Fe(VI)@PCN@BSA nanoparticles, and (d) elemental mapping of Fe(VI)@PCN@BSA nanoparticles
XRD patterns of K2FeO4, PCN-224, Fe(VI)@PCN-224, and Fe(VI)@PCN@BSA nanoparticles
DLS size distributions of (a) PCN-224, (b) Fe(VI)@PCN-224 and (c) Fe(VI)@PCN@BSA nanoparticles, and (d) Zeta potentials of BSA, PCN-224, Fe(VI)@PCN, and Fe(VI)@PCN@BSA nanoparticles
Changes of (a) size and (b) Zeta potential of Fe(VI)@PCN@BSA nanoparticles in H2O, PBS and DEME
(a) UV-Vis absorption spectra of PCN-224, Fe(VI)@PCN-224, and Fe(VI)@PCN@BSA suspensions (inset is pictures of the suspensions), and (b) Fourier transform infrared spectra of BSA, PCN-224, Fe(VI)@PCN-224, and Fe(VI)@PCN@BSA nanoparticles
Chemodynamic properties of Fe(VI)@PCN@BSA nanoparticles
Changes of dissolved O2 in NaAc solutions under (a) pH 6.0 and (b) pH 7.4 with different H2O2 concentrations after the addition of Fe(VI)@PCN@BSA nanoparticles (50 μg/mL)
(a-c) UV-Vis absorbance spectra of the DPBF solutions with Fe(VI)@PCN@BSA nanoparticles (50 μg/mL) and (d) absorbance changes of DPBF solutions at 439 nm for different groups
Cell viabilities of MDA-MB-231 cells and human dermal fibroblasts after 24 h incubation with Fe(VI)@PCN@BSA nanoparticles at different concentrations
Fluorescence images of MDA-MB-231 cells after different treatments for observing intracellular ROS
Synergistic therapeutic effect of Fe(VI)@PCN@BSA nanoparticles on MDA-MB-231 cells (*P P P < 0.001)
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Yuwei WANG, Jiajie CHEN, Zhengfang TIAN, Min ZHU, Yufang ZHU. Potassium Ferrate-loaded Porphyrin-based (VI) Metal-organic Frameworks for Combined Photodymanic and Chemodynamic Tumor Therapy[J]. Journal of Inorganic Materials, 2021, 36(12): 1305

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Paper Information

Category: EDITORIAL

Received: Mar. 12, 2021

Accepted: --

Published Online: Sep. 16, 2022

The Author Email: Yuwei WANG (676627664@qq.com)

DOI:10.15541/jim20210157

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