NUCLEAR TECHNIQUES, Volume. 48, Issue 4, 040301(2025)
Dosimetric effect of respiratory motion on boron neutron capture therapy for lung cancer
Fig. 1. Schematic diagram of Boron neutron capture therapy principle
Fig. 2. Illustration of multi-function and generalized intelligent code-bench based on Monte Carlo method
Fig. 3. Diagram of the three-dimensional spatial motion trajectory of lung tumors at different respiratory phases under respiratory motion conditions
Fig. 5. Sagittal and transverse sections of the adult male phantom
Fig. 6. (a) The energy spectrum distribution of neutron flux density at the exit of the epithermal neutron beam duct; (b) The angular distribution of group neutron current density at the exit of the epithermal neutron beam duct; (c) The energy spectrum distribution of photon flux density at the exit of the epithermal neutron beam duct; (d) The angular distribution of the group photon current density at the exit of the epithermal neutron beam duct
Fig. 7. Contribution and variation with energy of different elements to the neutron energy release ratio in adult lung tissue (color online)
Fig. 8. Dose rate values of dose components for each organ at the reference phase (color online)
Fig. 9. Total relative biological effect dose rate and dose percentage difference of tumor at different phases in various directions under respiratory motion conditions (a) LR, (b) AP, (c) SI
Fig. 10. The statistical errors of dose components for tumors at different phases in various directions under respiratory motion conditions
Fig. 11. Total relative biological effect dose rate and dose percentage difference of healthy tissues at different phases in various directions under respiratory motion conditions (color online) (a) Right lung, (b) Left lung, (c) Heart, (d) Liver, (e) Kidney, (f) Thyroid, (g) Skin
Fig. 12. Statistical error of dose components for healthy tissue organs at different phases in various directions under respiratory motion conditions (color online) (a) LR, (b) AP, (c) SI
Fig. 13. Dose field maps of the chest at the reference phase and the 50% phase (color online) (a) The 20% phase in the LR direction, (b) The 50% phase in the LR direction, (c) The 20% phase in the AP direction, (d) The 50% phase in the AP direction, (e) The 20% phase in the SI direction, (f) The 50% phase in the SI direction
Fig. 14. Total relative biological effect dose rate of tumor and healthy tissues during one cycle under respiratory motion condition (color online) (a) LR, (b) AP, (c) SI
Fig. 15. Dose error in three-dimensional directions considering and not considering respiratory motion conditions (color online)
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Lin ZHU, Tao YU, Aikou SUN, Kekun GAO, Hongyu QU, Tong LIU, Song WANG, Zizhu ZHANG, Yizheng CHONG, Zhenping CHEN. Dosimetric effect of respiratory motion on boron neutron capture therapy for lung cancer[J]. NUCLEAR TECHNIQUES, 2025, 48(4): 040301
Category: NUCLEAR CHEMISTRY, RADIOCHEMISTRY, RADIOPHARMACEUTICALS AND NUCLEAR MEDICINE
Received: Jul. 2, 2024
Accepted: --
Published Online: Jun. 3, 2025
The Author Email: Zhenping CHEN (陈珍平)