Chinese Journal of Lasers, Volume. 45, Issue 4, 407006(2018)
Simulation of Bioluminescence Tomography Based on Nonconvex L1-2 Regularization
Figures & Tables(8)
Fig. 1. (a) Digital mouse model and source setting in single-source case; (b) surface intensity distribution generated by forward simulation
Fig. 2. Comparison of reconstruction results in single-source case. 3D views of the reconstruction results by (a) L1-2, (b) IVTCG, (c) SpaRSA, (d) StOMP; transverse views at Z=19.2 mm of the reconstruction results by (e) L1-2, (f) IVTCG, (g) SpaRSA, (h) StOMP, where the red circle represents the real source
Fig. 3. (a) Digital mouse model and sources setting in double-source case; (b) surface intensity distribution generated by forward simulation
Fig. 4. Comparison of reconstruction results in double-source case. 3D views of the reconstruction results by (a) L1-2, (b) IVTCG, (c) SpaRSA, (d) StOMP; transverse views at Z=27.9 mm of the reconstruction results by (e) L1-2, (f) IVTCG, (g) SpaRSA, (h) StOMP, where the red circle represents the real source
Table 1. Optical parameters for the model of the digital mouse
View tableTable 1. Optical parameters for the model of the digital mouse
Parameter Muscle Heart Stomach Liver Kidney Lung μ a /mm-10.10 0.21 0.01 0.126 0.066 0.22 μ 's /mm-11.20 2.00 1.74 0.563 2.25 2.30
Table 2. Reconstruction results in single-source case
View tableTable 2. Reconstruction results in single-source case
Method Actual position center /mm Reconstruction position center /mm LE /mm T /sL 1-2(9.2,7.2,19.2) (9.21,7.59,18.99) 0.45 5.44 IVTCG (9.2,7.2,19.2) (9.54,7.64,18.64) 0.79 6.34 SpaRSA (9.2,7.2,19.2) (9.07,7.33,18.64) 0.59 2.75 StOMP (9.2,7.2,19.2) (10.27,7.13,19.92) 1.29 3.84
Table 3. Reconstruction results in double-source case
View tableTable 3. Reconstruction results in double-source case
Method Target Actual position center /mm Reconstruction position center /mm LE /mm T /sL 1-2Source 1 (9.6,15.3,27.9) (9.73,15.05,27.60) 0.41 Source 2 (12.5,15.3,27.9) (11.91,15.54,27.66) 0.68 3.73 IVTCG Source 1 (9.6,15.3,27.9) (9.79,14.86,27.74) 0.43 Source 2 (12.5,15.3,27.9) (11.80,15.25,27.49) 1.11 4.16 SpaRSA Source 1 (9.6,15.3,27.9) (11.56,14.84,27.53) 2.04 Source 2 (12.5,15.3,27.9) (11.82,15.11,27.54) 0.79 1.08 StOMP Source 1 (9.6,15.3,27.9) (10.46,16.14,29.53) 2.02 Source 2 (12.5,15.3,27.9) (12.39,16.47,28.32) 1.24 3.18
Table 4. Reconstruction results under different noise levels
View tableTable 4. Reconstruction results under different noise levels
Noise level /% Actual position center /mm Reconstruction position center /mm LE /mm T /s5 (9.2,7.2,19.2) (9.26,7.59,18.94) 0.47 6.73 10 (9.2,7.2,19.2) (9.23,7.61,18.89) 0.51 7.82 15 (9.2,7.2,19.2) (9.31,7.57,18.81) 0.55 9.66
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Yu Jingjing, Liu Jiale. Simulation of Bioluminescence Tomography Based on Nonconvex L1-2 Regularization[J]. Chinese Journal of Lasers, 2018, 45(4): 407006
Paper Information
Category: biomedical photonics and laser medicine
Received: Aug. 15, 2017
Accepted: --
Published Online: Apr. 13, 2018
The Author Email: Jingjing Yu (yujj@snnu.edu.cn)
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