Journal of Tongji University(Medical Science), Volume. 46, Issue 3, 311(2025)
Impact of virtual reality-based psychotherapy on negative attentional bias in individuals with depressive symptoms
[1] [1] MALHI G S, MANN J J. Depression[J]. Lancet, 2018, 392(10161): 2299-2312.
[2] [2] LEMOULT J, GOTLIB I H. Depression: a cognitive perspective[J]. Clin Psychol Rev, 2019, 69: 51-66.
[3] [3] KELLER A S, LEIKAUF J E, HOLT-GOSSELIN B, et al. Paying attention to attention in depression[J]. Transl Psychiatry, 2019, 9(1): 279.
[4] [4] WENZEL A. Basic strategies of cognitive behavioral therapy[J]. Psychiatr Clin North Am, 2017, 40(4): 597-609.
[5] [5] AJILCHI B, AHADI H, NAJATI V, et al. The efficacy of intensive short-term dynamic psychotherapy on attention bias in depressed patients[J]. Eur J Exp Biol, 2013, 3(3): 492-497.
[6] [6] VAZQUEZ C, DUQUE A, BLANCO I, et al. CBT and positive psychology interventions for clinical depression promote healthy attentional biases: an eyetracking study[J]. Depress Anxiety, 2018, 35(10): 966-973.
[7] [7] HOLAS P, KREJTZ I, WISIECKA K, et al. Modification of attentional bias to emotional faces following mindfulness-based cognitive therapy in people with a current depression[J]. Mindfulness, 2020, 11(6): 1413-1423.
[8] [8] GUPTA R S, KUJAWA A, FRESCO D M, et al. Mindfulness-based cognitive therapy: a preliminary examination of the (event-related) potential for modifying threat-related attentional bias in anxiety[J]. Mindfulness (N Y), 2022, 13(7): 1719-1732.
[9] [9] KOU H, LUO W, LIU X N, et al. Mindfulness training modifies attentional bias to facial emotion and emotional symptoms[J]. J Psychiatr Res, 2023, 167: 139-148.
[10] [10] GERAETS C N W, VAN DER STOUWE E C D, POT-KOLDER R, et al. Advances in immersive virtual reality interventions for mental disorders: a new reality?[J]. Curr Opin Psychol, 2021, 41: 40-45.
[11] [11] WIEBE A, KANNEN K, SELASKOWSKI B, et al. Virtual reality in the diagnostic and therapy for mental disorders: a systematic review[J]. Clin Psychol Rev, 2022, 98: 102213.
[12] [12] FREEMAN D, REEVE S, ROBINSON A, et al. Virtual reality in the assessment, understanding, and treatment of mental health disorders[J]. Psychol Med, 2017, 47(14): 2393-2400.
[13] [13] BAGHAEI N, CHITALE V, HLASNIK A, et al. Virtual reality for supporting the treatment of depression and anxiety: scoping review[J]. JMIR Ment Health, 2021, 8(9): e29681.
[14] [14] CIESLIK B, JUSZKO K, KIPER P, et al. Immersive virtual reality as support for the mental health of elderly women: a randomized controlled trial[J]. Virtual Real, 2023: 1-9.
[15] [15] PAUL M, BULLOCK K, BAILENSON J. Virtual reality behavioral activation for adults with major depressive disorder: feasibility randomized controlled trial[J]. JMIR Ment Health, 2022, 9(5): e35526.
[17] [17] STAMOU G, GARCIA-PALACIOS A, BOTELLA C. The combination of cognitive-behavioural therapy with virtual reality for the treatment of post-natal depression[C]//Proceedings of the 31st Australian Conference on Human-Computer-Interaction. Fremantle WA Australia. ACM, 2019: 599-603.
[18] [18] FERNANDEZ-ALVAREZ J, COLOMBO D, SUSORIBERA C, et al. Using virtual reality to target positive autobiographical memory in individuals with moderate-to-moderately severe depressive symptoms: a single case experimental design[J]. Internet Interv, 2021, 25: 100407.
[21] [21] HAMILTON M. A rating scale for depression[J]. J Neurol Neurosurg Psychiatry, 1960, 23(1): 56-62.
[23] [23] HAMILTON M. The assessment of anxiety states by rating[J]. Br J Med Psychol, 1959, 32(1): 50-55.
[24] [24] YANG B X, LIAO C X, YANG Y Q, et al. A virtual reality-based self-guided training on identification of negative automatic thoughts in healthy adults: a mixed-methods feasibility study[J]. Front Psychiatry, 2024, 15: 1479207.
[25] [25] FODOR L A, COTEȚ C D, CUIJPERS P, et al. The effectiveness of virtual reality based interventions for symptoms of anxiety and depression: a meta-analysis[J]. Sci Rep, 2018, 8(1): 10323.
[26] [26] MOBINI S, MACKINTOSH B, ILLINGWORTH J, et al. Effects of standard and explicit cognitive bias modification and computer-administered cognitive-behaviour therapy on cognitive biases and social anxiety[J]. J Behav Ther Exp Psychiatry, 2014, 45(2): 272-279.
[27] [27] HOFMANN S G, ASNAANI A, VONK I J J, et al. The efficacy of cognitive behavioral therapy: a review of meta-analyses[J]. Cognit Ther Res, 2012, 36(5): 427-440.
[28] [28] ROWLAND D P, CASEY L M, GANAPATHY A, et al. A decade in review: a systematic review of virtual reality interventions for emotional disorders[J]. Psychosoc Interv, 2021, 31(1): 1-20.
[30] [30] MOHLMAN J, PRICE R B, VIETRI J. Attentional bias in older adults: effects of generalized anxiety disorder and cognitive behavior therapy[J]. J Anxiety Disord, 2013, 27(6): 585-591.
[31] [31] SALUM G A, PETERSEN C S, JARROS R B, et al. Group cognitive behavioral therapy and attention bias modification for childhood anxiety disorders: a factorial randomized trial of efficacy[J]. J Child Adolesc Psychopharmacol, 2018, 28(9): 620-630.
[32] [32] HEITMANN J, VAN HEMEL-RUITER M E, HUISMAN M, et al. Effectiveness of attentional bias modification training as add-on to regular treatment in alcohol andCannabisuse disorder: a multicenter randomized control trial[J]. PLoS One, 2021, 16(6): e0252494.
[33] [33] SOLER IBORTE A, GALIANO RUS S, DAZ L. Placebo and placebo effect, variability of the clinical response according to the therapists' behavior[J]. Eur Psychiatr, 2016, 33(S1): S641-S642.
[34] [34] KIRSCH I. Placebo effect in the treatment of depression and anxiety[J]. Front Psychiatry, 2019, 10: 407.
[35] [35] WAMPOLD B E, MINAMI T, TIERNEY S C, et al. The placebo is powerful: estimating placebo effects in medicine and psychotherapy from randomized clinical trials[J]. J Clin Psychol, 2005, 61(7): 835-854.
[36] [36] WAGER T D, ATLAS L Y. The neuroscience of placebo effects: connecting context, learning and health[J]. Nat Rev Neurosci, 2015, 16(7): 403-418.
[37] [37] BENEDETTI F, CARLINO E, POLLO A. How placebos change the patient's brain[J]. Neuropsychophar-macology, 2011, 36(1): 339-354.
[38] [38] BEEVERS C G, CLASEN P C, ENOCK P M, et al. Attention bias modification for major depressive disorder: Effects on attention bias, resting state connectivity, and symptom change[J]. J Abnorm Psychol, 2015, 124(3): 463-475.
[39] [39] LEICHSENRING F. Comparative effects of short-term psychodynamic psychotherapy and cognitive-behavioral therapy in depression: a meta-analytic approach[J]. Clin Psychol Rev, 2001, 21(3): 401-419.
[40] [40] SUSANTY E, SIJBRANDIJ M, VAN DIJK W, et al. The effects of psychological interventions on neurocog-nitive functioning in posttraumatic stress disorder: a systematic review[J]. Eur J Psychotraumatol, 2022, 13(1): 2071527.
[41] [41] LOPES F M, PIRES A V, BIZARRO L. Attentional bias modification in smokers trying to quit: a longitudinal study about the effects of number of sessions[J]. J Subst Abuse Treat, 2014, 47(1): 50-57.
[42] [42] DE VOOGD E L, WIERS R W, SALEMINK E. Online visual search attentional bias modification for adolescents with heightened anxiety and depressive symptoms: a randomized controlled trial[J]. Behav Res Ther, 2017, 92: 57-67.
[43] [43] KRISTENSEN T D, MANDL R C W, JEPSEN J R M, et al. Non-pharmacological modulation of cerebral white matter organization: a systematic review of non-psychiatric and psychiatric studies[J]. Neurosci Biobehav Rev, 2018, 88: 84-97.
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LIAO Chenxi, YANG Bixi, YANG Yuqing, ZHANG Caidi, ZHU Zhipei, SHI Binbin, LI Chunbo. Impact of virtual reality-based psychotherapy on negative attentional bias in individuals with depressive symptoms[J]. Journal of Tongji University(Medical Science), 2025, 46(3): 311
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Received: Dec. 1, 2024
Accepted: Aug. 26, 2025
Published Online: Aug. 26, 2025
The Author Email: LI Chunbo (licb@smhc.org.cn)