[1] [1] CHEN Anqi, YUAN Na, ZHAO Weiwei, et al. Research progress in the mechanism of high-mobility group protein B-1 regulating the radiosensitivity of colorectal cancer［J］. Shandong Pharmaceutical, 2022, 62(12): 107-111.

[2] [2] JI D B, ZHAN T C, LI M, et al. Enhancement of sensitivity to chemo/radiation therapy by using miR-15b against DCLK1 in colorectal cancer［J］. Stem Cell Reports, 2018, 11(6): 1506-1522.

[3] [3] SHI L P, GUO H L, SU Y B, et al. MicroRNA-149 sensitizes colorectal cancer to radiotherapy by downregulating human epididymis protein 4［J］. American Journal of Cancer Research, 2018, 8(1): 30-38.

[4] [4] CHEN L, ZHU Z, GAO W, et al. Systemic analysis of different colorectal cancer cell lines and TCGA datasets identified IGF-1R/EGFR-PPAR-CASPASE axis as important indicator for radiotherapy sensitivity［J］. Gene, 2017, 627: 484-490.

[5] [5] DUONG J, STEWARD-LORD A, NARIYANGADU P, et al. PH-0494 treatment outcomes of stereotactic ablative radiotherapy on oligometastases from colorectal cancer［J］. Radiotherapy and Oncology, 2021, 161(S1): 20210071.

[6] [6] FLAMARIQUE S, CAMPO M, ASIN G, et al. Stereotactic body radiation therapy for liver metastasis from colorectal cancer: size matters［J］. Clinical & Translational Oncology, 2020, 22(12): 2350-2356.

[7] [7] FU K, ZHANG K, ZHANG X Y. LncRNA HOTAIR facilitates proliferation and represses apoptosis of retinoblastoma cells through the miR-20b-5p/RRM2/PI3K/AKT axis［J］. Orphanet Journal of Rare Diseases, 2022, 17(1): 119.

[8] [8] SHAN J L, WANG Z, MO Q P, et al. Ribonucleotide reductase M2 subunit silencing suppresses tumorigenesis in pancreatic cancer via inactivation of PI3K/AKT/mTOR pathway［J］. Pancreatology, 2022, 22(3): 401-413.

[9] [9] TANG B F, XU W T, WANG Y J, et al. Identification of critical ferroptosis regulators in lung adenocarcinoma that RRM2 facilitates tumor immune infiltration by inhibiting ferroptotic death［J］.Clinical Immunology, 2021, 232: 108872.

[10] [10] XIONG W, ZHANG B, YU H X, et al. RRM2 regulates sensitivity to sunitinib and PD-1 blockade in renal cancer by stabilizing ANXA1 and activating the AKT pathway［J］. Advanced Science (Weinheim, Baden-Wurttemberg, Germany), 2021, 8(18): 2100881.

[11] [11] JIANG X P, LI Y Y, ZHANG N N, et al. RRM2 silencing suppresses malignant phenotype and enhances radiosensitivity via activating cGAS/STING signaling pathway in lung adenocarcinoma ［J］. Cell & Bioscience, 2021, 11(1): 74.

[12] [12] LIU Q, GUO L J, QI H Y, et al. A MYBL2 complex for RRM2 transactivation and the synthetic effect of MYBL2 knockdown with WEE1 inhibition against colorectal cancer［J］. Cell Death & Disease, 2021, 12(7): 683.

[13] [13] CHANG C C, LIN C C, WANG C H, et al. miR-211 regulates the expression of RRM2 in tumoral metastasis and recurrence in colorectal cancer patients with a k-ras gene mutation［J］. Oncology Letters, 2018, 15(5): 8107-8117.

[14] [14] MA J J, ZHANG F, SUN P. miR-140-3p impedes the proliferation of human cervical cancer cells by targeting RRM2 to induce cell-cycle arrest and early apoptosis［J］. Bioorganic & Medicinal Chemistry, 2019, 28(3): 115283.

[15] [15] GROLMUSZ V K, KARASZI K, MICSIK T, et al. Cell cycle dependent RRM2 may serve as proliferation marker and pharmaceutical target in adrenocortical cancer［J］. American Journal of Cancer Research, 2016, 6(9): 2041-2053.

[16] [16] YU Xiaosheng, ZHANG Yonghai, LIU Jinhao, et al. In vitro study of oleanolic acid combined with radiotherapy on HepG2 cell cycle and apoptosis［J］. Journal of Beihua University (Natural Science Edition), 2018, 19(4): 461-464.

[17] [17] YANG Tian, WU Balu, JIANG Hongqiang, et al. Experimental study on the mechanism of MAPK14 and radiotherapy resistance in gastric cancer［J］. Chinese Journal of Cancer Prevention and Treatment, 2019, 26(21): 1599-1605.

[18] [18] ZHAN Y, JIANG L, JIN X, et al. Inhibiting RRM2 to enhance the anticancer activity of chemotherapy［J］. Biomed Pharmacother, 2021, 133(23): 110996.

[19] [19] JIANG X, LI Y, ZHANG N, et al. RRM2 silencing suppresses malignant phenotype and enhances radiosensitivity via activating cGAS/STING signaling pathway in lung adenocarcinoma［J］. Cell and Bioscience, 2021, 11(1): 74.