Lensless polarimetric coded ptychography for high-resolution, high-throughput gigapixel birefringence imaging on a chip

Liming Yang; Ruihai Wang; Qianhao Zhao; Pengming Song; Shaowei Jiang; Tianbo Wang; Xiaopeng Shao; Chengfei Guo; Rishikesh Pandey; Guoan Zheng

doi:10.1364/PRJ.504378

Photonics Research, Volume. 11, Issue 12, 2242(2023)

Lensless polarimetric coded ptychography for high-resolution, high-throughput gigapixel birefringence imaging on a chip Author Presentation , Spotlight on Optics

Liming Yang^1,2、†, Ruihai Wang^2、†, Qianhao Zhao², Pengming Song², Shaowei Jiang², Tianbo Wang², Xiaopeng Shao^1,3、*, Chengfei Guo², Rishikesh Pandey², and Guoan Zheng^2,4、*

Author Affiliations

¹School of Optoelectronic Engineering, Xidian University, Xi’an 710071, China

²Department of Biomedical Engineering, University of Connecticut, Storrs, Connecticut 06269, USA

³e-mail: xpshao@xidian.edu.cn

⁴e-mail: guoan.zheng@uconn.edu

show less

References(58)

[1] C. He, H. He, J. Chang, B. Chen, H. Ma, M. J. Booth. Polarisation optics for biomedical and clinical applications: a review. Light Sci. Appl., 10, 194(2021).

[2] S. Alali, A. Vitkin. Polarized light imaging in biomedicine: emerging Mueller matrix methodologies for bulk tissue assessment. J. Biomed. Opt., 20, 061104(2015).

[3] R. Hristu, S. G. Stanciu, D. E. Tranca, G. A. Stanciu. Improved quantification of collagen anisotropy with polarization-resolved second harmonic generation microscopy. J. Biophoton., 10, 1171-1179(2017).

[4] A. Keikhosravi, M. Shribak, M. W. Conklin, Y. Liu, B. Li, A. Loeffler, R. M. Levenson, K. W. Eliceiri. Real-time polarization microscopy of fibrillar collagen in histopathology. Sci. Rep., 11, 19063(2021).

[5] C. W. Pirnstill, G. L. Coté. Malaria diagnosis using a mobile phone polarized microscope. Sci. Rep., 5, 13368(2015).

[6] D. Keefe, L. Liu, W. Wang, C. Silva. Imaging meiotic spindles by polarization light microscopy: principles and applications to IVF. Reprod. Biomed. Online, 7, 24-29(2003).

[7] N. W. McGill, P. A. Dieppe. Evidence for a promoter of urate crystal formation in gouty synovial fluid. Ann. Rheum. Dis., 50, 558-561(1991).

[8] R. Sharma, S. Rehani, M. Mehendiratta, P. Kardam, M. Kumra, Y. Mathias, J. Yadav, K. Sahay. Architectural analysis of picrosirius red stained collagen in oral epithelial dysplasia and oral squamous cell carcinoma using polarization microscopy. J. Clin. Diagn. Res., 9, EC13-EC16(2015).

[9] O. Warszawik-Hendzel, M. Olszewska, M. Maj, A. Rakowska, J. Czuwara, L. Rudnicka. Non-invasive diagnostic techniques in the diagnosis of squamous cell carcinoma. J. Dermatol. Case Rep., 9, 89-97(2015).

[10] J. Rieppo, J. Hallikainen, J. S. Jurvelin, I. Kiviranta, H. J. Helminen, M. M. Hyttinen. Practical considerations in the use of polarized light microscopy in the analysis of the collagen network in articular cartilage. Microsc. Res. Tech., 71, 279-287(2008).

[11] L.-W. Jin, K. A. Claborn, M. Kurimoto, M. A. Geday, I. Maezawa, F. Sohraby, M. Estrada, W. Kaminksy, B. Kahr. Imaging linear birefringence and dichroism in cerebral amyloid pathologies. Proc. Natl. Acad. Sci. USA, 100, 15294-15298(2003).

[12] K. Park, T. D. Yang, D. Seo, M. G. Hyeon, T. Kong, B.-M. Kim, Y. Choi, W. Choi, Y. Choi. Jones matrix microscopy for living eukaryotic cells. ACS Photon., 8, 3042-3050(2021).

[13] J. Park, D. J. Brady, G. Zheng, L. Tian, L. Gao. Review of bio-optical imaging systems with a high space-bandwidth product. Adv. Photon., 3, 044001(2021).

[14] G. Zheng, C. Shen, S. Jiang, P. Song, C. Yang. Concept, implementations and applications of Fourier ptychography. Nat. Rev. Phys., 3, 207-223(2021).

[15] Z. Bian, C. Guo, S. Jiang, J. Zhu, R. Wang, P. Song, Z. Zhang, K. Hoshino, G. Zheng. Autofocusing technologies for whole slide imaging and automated microscopy. J. Biophoton., 13, e202000227(2020).

[16] N. Farahani, A. V. Parwani, L. Pantanowitz. Whole slide imaging in pathology: advantages, limitations, and emerging perspectives. Pathol. Lab. Med. Int., 7, 23-33(2015).

[17] P. Ferrand, M. Allain, V. Chamard. Ptychography in anisotropic media. Opt. Lett., 40, 5144-5147(2015).

[18] P. Ferrand, A. Baroni, M. Allain, V. Chamard. Quantitative imaging of anisotropic material properties with vectorial ptychography. Opt. Lett., 43, 763-766(2018).

[19] A. Baroni, V. Chamard, P. Ferrand. Extending quantitative phase imaging to polarization-sensitive materials. Phys. Rev. Appl., 13, 054028(2020).

[20] G. Zheng, R. Horstmeyer, C. Yang. Wide-field, high-resolution Fourier ptychographic microscopy. Nat. Photonics, 7, 739-745(2013).

[21] S. Song, J. Kim, S. Hur, J. Song, C. Joo. Large-area, high-resolution birefringence imaging with polarization-sensitive Fourier ptychographic microscopy. ACS Photon., 8, 158-165(2021).

[22] X. Dai, S. Xu, X. Yang, K. C. Zhou, C. Glass, P. C. Konda, R. Horstmeyer. Quantitative Jones matrix imaging using vectorial Fourier ptychography. Biomed. Opt. Express, 13, 1457-1470(2022).

[23] C. Guo, Z. Bian, S. Jiang, M. Murphy, J. Zhu, R. Wang, P. Song, X. Shao, Y. Zhang, G. Zheng. OpenWSI: a low-cost, high-throughput whole slide imaging system via single-frame autofocusing and open-source hardware. Opt. Lett., 45, 260-263(2020).

[24] T. Wang, S. Jiang, P. Song, R. Wang, L. Yang, T. Zhang, G. Zheng. Optical ptychography for biomedical imaging: recent progress and future directions. Biomed. Opt. Express, 14, 489-532(2023).

[25] S. Dong, R. Horstmeyer, R. Shiradkar, K. Guo, X. Ou, Z. Bian, H. Xin, G. Zheng. Aperture-scanning Fourier ptychography for 3D refocusing and super-resolution macroscopic imaging. Opt. Express, 22, 13586-13599(2014).

[26] H. Zhang, S. Jiang, J. Liao, J. Deng, J. Liu, Y. Zhang, G. Zheng. Near-field Fourier ptychography: super-resolution phase retrieval via speckle illumination. Opt. Express, 27, 7498-7512(2019).

[27] L. Tian, L. Waller. 3D intensity and phase imaging from light field measurements in an LED array microscope. Optica, 2, 104-111(2015).

[28] R. Horstmeyer, J. Chung, X. Ou, G. Zheng, C. Yang. Diffraction tomography with Fourier ptychography. Optica, 3, 827-835(2016).

[29] A. M. Maiden, M. J. Humphry, J. Rodenburg. Ptychographic transmission microscopy in three dimensions using a multi-slice approach. J. Opt. Soc. Am. A, 29, 1606-1614(2012).

[30] Z. Zhang, Y. Zhou, S. Jiang, K. Guo, K. Hoshino, J. Zhong, J. Suo, Q. Dai, G. Zheng. Invited article: mask-modulated lensless imaging with multi-angle illuminations. APL Photon., 3, 060803(2018).

[31] C. Lu, Y. Zhou, Y. Guo, S. Jiang, Z. Zhang, G. Zheng, J. Zhong. Mask-modulated lensless imaging via translated structured illumination. Opt. Express, 29, 12491-12501(2021).

[32] J. Kim, S. Song, B. Kim, M. Park, S. J. Oh, D. Kim, B. Cense, Y.-M. Huh, J. Y. Lee, C. Joo. Ptychographic lens-less polarization microscopy. arXiv preprint(2022).

[33] H. Zhang, Z. Bian, S. Jiang, J. Liu, P. Song, G. Zheng. Field-portable quantitative lensless microscopy based on translated speckle illumination and sub-sampled ptychographic phase retrieval. Opt. Lett., 44, 1976-1979(2019).

[34] P. Li, A. Maiden. Lensless LED matrix ptychographic microscope: problems and solutions. Appl. Opt., 57, 1800-1806(2018).

[35] M. Stockmar, P. Cloetens, I. Zanette, B. Enders, M. Dierolf, F. Pfeiffer, P. Thibault. Near-field ptychography: phase retrieval for inline holography using a structured illumination. Sci. Rep., 3, 1927(2013).

[36] Y. Zhang, S. Y. C. Lee, Y. Zhang, D. Furst, J. Fitzgerald, A. Ozcan. Wide-field imaging of birefringent synovial fluid crystals using lens-free polarized microscopy for gout diagnosis. Sci. Rep., 6, 28793(2016).

[37] M. J. Lopera, C. Trujillo. Linear diattenuation imaging of biological samples with digital lensless holographic microscopy. Appl. Opt., 61, B77-B82(2022).

[38] Y. Zhou, B. Xiong, X. Li, Q. Dai, X. Cao. Lensless imaging of plant samples using the cross-polarized light. Opt. Express, 28, 31611-31623(2020).

[39] T. Liu, K. de Haan, B. Bai, Y. Rivenson, Y. Luo, H. Wang, D. Karalli, H. Fu, Y. Zhang, J. FitzGerald. Deep learning-based holographic polarization microscopy. ACS Photon., 7, 3023-3034(2020).

[40] X. Liu, Y. Yang, L. Han, C.-S. Guo. Fiber-based lensless polarization holography for measuring Jones matrix parameters of polarization-sensitive materials. Opt. Express, 25, 7288-7299(2017).

[41] C. Guo, S. Jiang, P. Song, T. Wang, X. Shao, Z. Zhang, G. Zheng. Quantitative multi-height phase retrieval via a coded image sensor. Biomed. Opt. Express, 12, 7173-7184(2021).

[42] S. Jiang, C. Guo, P. Song, T. Wang, R. Wang, T. Zhang, Q. Wu, R. Pandey, G. Zheng. High-throughput digital pathology via a handheld, multiplexed, and AI-powered ptychographic whole slide scanner. Lab Chip, 22, 2657-2670(2022).

[43] C. Zuo, J. Li, J. Sun, Y. Fan, J. Zhang, L. Lu, R. Zhang, B. Wang, L. Huang, Q. Chen. Transport of intensity equation: a tutorial. Opt. Laser Eng., 106187(2020).

[44] S. Jiang, C. Guo, P. Song, N. Zhou, Z. Bian, J. Zhu, R. Wang, P. Dong, Z. Zhang, J. Liao, J. Yao, B. Feng, M. Murphy, G. Zheng. Resolution-enhanced parallel coded ptychography for high-throughput optical imaging. ACS Photon., 8, 3261-3271(2021).

[45] S. Jiang, C. Guo, Z. Bian, R. Wang, J. Zhu, P. Song, P. Hu, D. Hu, Z. Zhang, K. Hoshino. Ptychographic sensor for large-scale lensless microbial monitoring with high spatiotemporal resolution. Biosens. Bioelectron., 196, 113699(2022).

[46] S. Jiang, C. Guo, T. Wang, J. Liu, P. Song, T. Zhang, R. Wang, B. Feng, G. Zheng. Blood-coated sensor for high-throughput ptychographic cytometry on a Blu-ray disc. ACS Sens., 7, 1058-1067(2022).

[47] C. Guo, S. Jiang, L. Yang, P. Song, A. Pirhanov, R. Wang, T. Wang, X. Shao, Q. Wu, Y. K. Cho. Depth-multiplexed ptychographic microscopy for high-throughput imaging of stacked bio-specimens on a chip. Biosens. Bioelectron., 224, 115049(2023).

[48] S. Jiang, P. Song, T. Wang, L. Yang, R. Wang, C. Guo, B. Feng, A. Maiden, G. Zheng. Spatial- and Fourier-domain ptychography for high-throughput bio-imaging. Nat. Protoc., 18, 2051-2083(2023).

[49] S. Jiang, J. Zhu, P. Song, C. Guo, Z. Bian, R. Wang, Y. Huang, S. Wang, H. Zhang, G. Zheng. Wide-field, high-resolution lensless on-chip microscopy via near-field blind ptychographic modulation. Lab Chip, 20, 1058-1065(2020).

[50] P. Song, R. Wang, J. Zhu, T. Wang, Z. Bian, Z. Zhang, K. Hoshino, M. Murphy, S. Jiang, C. Guo. Super-resolved multispectral lensless microscopy via angle-tilted, wavelength-multiplexed ptychographic modulation. Opt. Lett., 45, 3486-3489(2020).

[51] T. Wang, P. Song, S. Jiang, R. Wang, L. Yang, C. Guo, Z. Zhang, G. Zheng. Remote referencing strategy for high-resolution coded ptychographic imaging. Opt. Lett., 48, 485-488(2023).

[52] A. Maiden, D. Johnson, P. Li. Further improvements to the ptychographical iterative engine. Optica, 4, 736-745(2017).

[53] P. Song, C. Guo, S. Jiang, T. Wang, P. Hu, D. Hu, Z. Zhang, B. Feng, G. Zheng. Optofluidic ptychography on a chip. Lab Chip, 21, 4549-4556(2021).

[54] R. A. Gatter. The Compensated Polarized Light Microscope in Clinical Rheumatology, 253-255(1974).

[55] K. S. Wong, J. S. Lewis, S. Gottipati, R. D. Chernock. Utility of birefringent crystal identification by polarized light microscopy in distinguishing thyroid from parathyroid tissue on intraoperative frozen sections. Am. J. Surg. Pathol., 38, 1212-1219(2014).

[56] E. Estève, D. Buob, F. Jamme, C. Jouanneau, S. Kascakova, J.-P. Haymann, E. Letavernier, L. Galmiche, P. Ronco, M. Daudon. Detection and localization of calcium oxalate in kidney using synchrotron deep ultraviolet fluorescence microscopy. J. Synchrotron Radiat., 29, 214-223(2022).

[57] Y. Wang, H. He, J. Chang, C. He, S. Liu, M. Li, N. Zeng, J. Wu, H. Ma. Mueller matrix microscope: a quantitative tool to facilitate detections and fibrosis scorings of liver cirrhosis and cancer tissues. J. Biomed. Opt., 21, 071112(2016).

[58] Y. Dong, J. Qi, H. He, C. He, S. Liu, J. Wu, D. S. Elson, H. Ma. Quantitatively characterizing the microstructural features of breast ductal carcinoma tissues in different progression stages by Mueller matrix microscope. Biomed. Opt. Express, 8, 3643-3655(2017).

Tools

Get Citation

Copy Citation Text

Liming Yang, Ruihai Wang, Qianhao Zhao, Pengming Song, Shaowei Jiang, Tianbo Wang, Xiaopeng Shao, Chengfei Guo, Rishikesh Pandey, Guoan Zheng, "Lensless polarimetric coded ptychography for high-resolution, high-throughput gigapixel birefringence imaging on a chip," Photonics Res. 11, 2242 (2023)

Download Citation

EndNote(RIS)BibTex Plain Text

Set citation alerts for article

Save article for my favorites

Paper Information

Category: Imaging Systems, Microscopy, and Displays

Received: Aug. 29, 2023

Accepted: Oct. 7, 2023

Published Online: Dec. 1, 2023

The Author Email: Xiaopeng Shao (xpshao@xidian.edu.cn), Guoan Zheng (guoan.zheng@uconn.edu)

DOI:10.1364/PRJ.504378

Topics

laser devices and laser physics

Lasers and Laser Optics

Laser physics

laser manufacturing

Instrumentation, Measurement and Metrology