Flavour Fragrance Cosmetics, Volume. , Issue 3, 24(2025)

Separation and Purification of Oleuropein from Leaves of Olea Europaea by Macroporous Resin

WU Qian1,2, ZHAO Jun3, and SONG Yunfei3、*
Author Affiliations
  • 1Shanghai Qiran Biotechnology Co., Ltd., Shanghai 201702, China
  • 2Shanghai Jinjia Technology Co., Ltd., Shanghai 201210, China
  • 3Guilin Layn Natural Ingredients Corp., Guilin 541199, Guangxi, China
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    References(9)

    [1] [1] LIU B Q, LIU J F, HUANG D D,et al. Separation and purification of hydroxytysol and oleuropein fromOlea europaeaL. (olive) leaves using macroporous resins and a novel solvent system [J]. Journal of Separation Science, 2020, 43(13): 2619-2625.

    [2] [2] ELHRECH H, AGUERD O, EL KOURCHI C,et al. Comprehensive review ofOlea europaea: a holistic exploration into its botanical marvels, phytochemical riches, therapeutic potentials, and safety profile [J]. Biomolecules, 2024, 14(6): 722.

    [4] [4] XYNOS N, PAPAEFSTATHIOU G, GIKAS E,et al. Design optimization study of the extraction of olive leaves performed with pressurized liquid extraction using response surface methodology [J]. Separation and Purification Technology, 2014, 122: 323-330.

    [5] [5] WANG X F, LI C, SHI Y P,et al. Two new secoiridoid glycosides from the leaves ofOlea europaeaL. [J]. Journal of Asian Natural Products Research, 2009, 11(11): 940-944.

    [7] [7] ZCAN A A, DEMIRLI . Molecular imprinted solid-phase extraction system for the selective separation of oleuropein from olive leaf [J]. Separation Science and Technology, 2014, 49(1): 74-80.

    [8] [8] ZHANG J, HUANG X Y, SUN X M,et al. Efficient method for the screening and identification of anti-diabetic components in the leaves ofOlea europaeaL. [J]. New Journal of Chemistry, 2014, 38(8): 3796-3802.

    [9] [9] KHEMAKHEM I, AHMAD-QASEM M H, CATALN E B,et al. Kinetic improvement of olive leaves’ bioactive compounds extraction by using power ultrasound in a wide temperature range [J]. Ultrasonics Sonochemistry, 2017, 34: 466-473.

    [10] [10] OTERO D M, OLIVEIRA F M, LORINI A,et al. Oleuropein: methods for extraction, purifying and applying [J]. Revista Ceres, 2020, 67(4): 315-329.

    [20] [20] SIVAKUMAR G, UCCELLA N A, GENTILE L. Probing downstream olive biophenol secoiridoids [J]. International Journal of Molecular Sciences, 2018, 19(10): 2892.

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    WU Qian, ZHAO Jun, SONG Yunfei. Separation and Purification of Oleuropein from Leaves of Olea Europaea by Macroporous Resin[J]. Flavour Fragrance Cosmetics, 2025, (3): 24

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    Paper Information

    Category:

    Received: Nov. 12, 2024

    Accepted: Aug. 26, 2025

    Published Online: Aug. 26, 2025

    The Author Email: SONG Yunfei (song.yunfei@layn.com.cn)

    DOI:10.20099/j.issn.1000-4475.2024.0338

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