Chinese Journal of Lasers, Volume. 47, Issue 2, 207025(2020)
Identification of Human Coronary Atherosclerotic Plaques using Spectrum- and Time-Resolved Multiphoton Microscopy
Fig. 1. Spectrum-coded images with different depths and the corresponding 3D images and histology of CAP and non-CAP regions in human coronary arterial intima. (a) Spectrum-coded images; (b) 3D structure images; (c) pathological images. The right color band represents the range of spectral: 404.58--592.08 nm
Fig. 2. Spectral characteristics of the multiple components of the normal and diseased human intima of coronary artery. (a) TPEF spectra of non-CAP and CAP regions; (b) ratio of TPEF to SHG signal from non-CAP and CAP regions of eight samples(**means 0.001<P<0.01, P represents significance level)
Fig. 3. Fluorescence lifetime-code images with different depths of the non-CAP and CAP lesion human coronary arterial intima. The right color band represents the range of spectral fluorescence lifetime: 0.5--2.5 ns
Fig. 4. Quantitative fluorescence lifetime of the biochemical components of normal and AP regions from human coronary arterial wall (*** means P<0.001)
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Zhang Rongli, Li Hui, Wu Yueheng, Yu Jia, Liu Shangmin, Zheng Wei, Lin Zhanyi. Identification of Human Coronary Atherosclerotic Plaques using Spectrum- and Time-Resolved Multiphoton Microscopy[J]. Chinese Journal of Lasers, 2020, 47(2): 207025
Category: biomedical photonics and laser medicine
Received: Oct. 8, 2019
Accepted: --
Published Online: Feb. 21, 2020
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