Laser & Optoelectronics Progress, Volume. 59, Issue 6, 0617024(2022)
Preliminary Exploration of Plasmon-Enhanced Four-Wave Mixing Imaging and Its Possible Application in Antibody-Drug Metabolism in the Body
Fig. 1. Multi-mode nonlinear optical imaging system. (a) Schematic diagram of the structure design of the multi-mode nonlinear optical imaging system; (b) picture of Olympus FVMPE-RS microscope
Fig. 2. Test for two-photon imaging function. (a) Two-photon imaging of anthracene crystals; (b) two-photon fluorescence spectra of anthracene crystals
Fig. 3. Test for SRS imaging function. (a) Bright field imaging of PMMA; (b) SRS imaging effect; (c) Raman spectra of PMMA
Fig. 4. Optimization of SRS resonance conditions. (a) SRS images of PMMA varying with the delay time of two wavelength lasers; (b) SRS images of PMMA associated with the pump laser wavelength
Fig. 5. Schematic diagram of plasmon enhanced FWM. (a) Diagram showing the coupling of surface plasmon resonance for energy levels for FWM; (b) local electromagnetic field simulations of Ag and Au nanoparticles in FWM; (c) FWM image of metal nanoparticles recorded by the self-built multi-photon microscope
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Yijia Geng, Lili Cong, Xiumian Cao, Xin Guan, Zepeng Huo, Gang Chen, Yu Liu, Weiqing Xu, Chongyang Liang, Shuping Xu. Preliminary Exploration of Plasmon-Enhanced Four-Wave Mixing Imaging and Its Possible Application in Antibody-Drug Metabolism in the Body[J]. Laser & Optoelectronics Progress, 2022, 59(6): 0617024
Category: Medical Optics and Biotechnology
Received: Nov. 29, 2021
Accepted: Jan. 17, 2022
Published Online: Mar. 8, 2022
The Author Email: Weiqing Xu (xuwq@jlu.edu.cn), Chongyang Liang (liang@jlu.edu.cn), Shuping Xu (xusp@jlu.edu.cn)